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Literature summary for 3.4.11.9 extracted from
- Aminopeptidase-P (1968), Biochem. Biophys. Res. Commun., 32, 658-663.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | 0.1-1 mM, completely | Escherichia coli |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mn2+ | activates, sharp optimum at 0.37 mM | Escherichia coli | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 230000 | - |
equilibrium sedimentation | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
| Escherichia coli B / ATCC 11303 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Ala-Pro + H2O | - |
Escherichia coli | Ala + Pro | - |
? | |
| Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg + H2O | i.e. bradykinin | Escherichia coli | Arg + Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg | one Arg is released per mol of bradykinin in less than 5 min, the following Pro residue is released within 1 h | ? | |
| Gly-Pro + H2O | - |
Escherichia coli | Gly + Pro | - |
? | |
| Gly-Pro + H2O | - |
Escherichia coli B / ATCC 11303 | Gly + Pro | - |
? | |
| Gly-Pro-Gly-Gly + H2O | - |
Escherichia coli | ? | - |
? | |
| Gly-Pro-Gly-Gly + H2O | - |
Escherichia coli B / ATCC 11303 | ? | - |
? | |
| papain + H2O | reduced and carboxymethylated, with the N-terminal sequence Ile-Pro-Glu-Tyr-Val | Escherichia coli | ? | - |
? | |
| Pro-Pro + H2O | - |
Escherichia coli | Pro | - |
? | |
| Pro-Pro + H2O | - |
Escherichia coli B / ATCC 11303 | Pro | - |
? | |
| Pro-Pro-Ala + H2O | - |
Escherichia coli | ? | - |
? | |
| Pro-Pro-Ala + H2O | - |
Escherichia coli B / ATCC 11303 | ? | - |
? | |
| Val-Pro + H2O | - |
Escherichia coli | Val + Pro | - |
? | |
| Val-Pro + H2O | - |
Escherichia coli B / ATCC 11303 | Val + Pro | - |
? | |
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