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Literature summary for 3.4.11.7 extracted from

  • Nagatsu, I.; Nagatsu, T.; Yamamoto, T.; Glenner, G.G.; Mehl, J.W.
    Purification of aminopeptidase A in human serum and degradation of angiotensin II by the purified enzyme (1970), Biochim. Biophys. Acta, 198, 255-270.
    View publication on PubMed
Search for more literature for 3.4.11.7

Inhibitors

Inhibitors Comment Organism Structure
amastatin stereoisomers and analogues Homo sapiens
EDTA
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.091 1.2 Glu-beta-naphthylamide value depending on source of enzyme and presence of divalent cations Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ba2+ activation Homo sapiens
Ca2+ activation Homo sapiens
Sr2+ activation Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
190000
-
 gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
preparation with 10% leucyl-beta-naphthylaminidase Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-L-Asp-Val-angiotensin II + H2O
-
 Homo sapiens Asp + Val-angiotensin II
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Homo sapiens