Literature summary for 3.4.11.6 extracted from

Ye, M.; Wysocki, J.; Gonzalez-Pacheco, F.R.; Salem, M.; Evora, K.; Garcia-Halpin, L.; Poglitsch, M.; Schuster, M.; Batlle, D.
Murine recombinant angiotensin-converting enzyme 2: effect on angiotensin II-dependent hypertension and distinctive angiotensin-converting enzyme 2 inhibitor characteristics on rodent and human angiotensin-converting enzyme 2 (2012), Hypertension, 60, 730-740.

Search for more literature for 3.4.11.6

Inhibitors

Inhibitors	Comment	Organism	Structure
DX600	only blocks human ACE2 activity but not mouse	Homo sapiens
MLN-4760	MLN-4760 inhibits both human and mouse ACE2	Homo sapiens
MLN-4760	MLN-4760 inhibits both human and mouse ACE2	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Mus musculus	-	-	-

Synonyms

Synonyms	Comment	Organism
ACE2	-	Mus musculus
ACE2	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	when murine ACE2 is given to mice for 4 weeks, a marked increase in serum ACE2 activity is detected. ACE2 leads to the dissipation of Ang II with formation of Ang (1-7)	Mus musculus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)