Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.11.6 extracted from

  • Piesse, C.; Cadel, S.; Gouzy-Darmon, C.; Jeanny, J.C.; Carriere, V.; Goidin, D.; Jonet, L.; Gourdji, D.; Cohen, P.; Foulon, T.
    Expression of aminopeptidase B in the developing and adult rat retina (2004), Exp. Eye Res., 79, 639-648.
    View publication on PubMed
Search for more literature for 3.4.11.6

Inhibitors

Inhibitors Comment Organism Structure
Arphamenine B aminopeptidase B-specific inhibitor Rattus norvegicus
bestatin orally applicated inhibits the melanoma cell-induced angiogenesis in mice air sacs Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus the enzyme plays a role in peptide or protein precursor processing, the enzyme expression is up-regulated during ontogenesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus O09175 Wistar rats, gene Ap-B
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
 Rattus norvegicus
-
additional information developmental expression and activity pattern of Ap-B, in-situ hydridization, overview Rattus norvegicus
-
neuronal cell retinal Rattus norvegicus
-
retina enzyme expression from embryo to adult rat, neuronal cell, developmental distribution, overview Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Arg-2-naphthylamide + H2O
-
 Rattus norvegicus L-Arg + 2-naphthylamine
-
 ?
additional information the enzyme plays a role in peptide or protein precursor processing, the enzyme expression is up-regulated during ontogenesis Rattus norvegicus ?
-
 ?
additional information the enzyme catalyzes the N-terminal cleavage of basic residues of peptide or protein substrates Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
Ap-B
-
 Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Rattus norvegicus