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Literature summary for 3.4.11.5 extracted from

  • Mäkinen, K.K.
    The proline iminopeptidases of human oral cavity (1969), Acta Chem. Scand., 23, 1409-1438.
No PubMed abstract available
Search for more literature for 3.4.11.5

Inhibitors

Inhibitors Comment Organism Structure
diphenylcarbamoyl chloride enzymes II and III oral microorganisms
L-Hydroxyprolyl-2-naphthylamide competitive oral microorganisms
N-ethylmaleimide
-
 oral microorganisms
p-chloromercuribenzoate
-
 oral microorganisms

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information dependency of Km on pH oral microorganisms

Metals/Ions

Metals/Ions Comment Organism Structure
additional information no metalloenzyme oral microorganisms

Organism

Organism UniProt Comment Textmining
oral microorganisms
-
 enzyme secreted into saliva
-

Purification (Commentary)

Purification (Comment) Organism
3 enzymes, II and III specific for naphthylamides of L-Pro and L-Hyp oral microorganisms

Source Tissue

Source Tissue Comment Organism Textmining
saliva
-
 oral microorganisms
-

Storage Stability

Storage Stability Organism
4°C, 8 weeks oral microorganisms

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-hydroxyproline-2-naphthylamide + H2O enzymes II and III oral microorganisms L-hydroxyproline + 2-naphthylamine
-
 ?
L-prolyl-peptide + H2O influence of amino acid adjacent to N-terminal L-Pro on rate of hydrolysis oral microorganisms L-proline + peptide
-
 ?
N-L-Pro-2-naphthylamide + H2O enzymes II and III specific for oral microorganisms L-proline + naphthylamine
-
 ?

pH Range

pH Minimum pH Maximum Comment Organism
6.5 8.5
-
 oral microorganisms