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Literature summary for 3.4.11.4 extracted from
- Aminotripeptidase, a cytosol enzyme from rabbit intestinal mucosa (1979), Biochem. J., 177, 801-808.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | - |
Oryctolagus cuniculus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.52 | - |
Ala-Ala-Ala | - |
Oryctolagus cuniculus | |
| 0.55 | - |
Leu-Gly-Gly | - |
Oryctolagus cuniculus | |
| 1.3 | - |
L-Pro-Gly-Gly | - |
Oryctolagus cuniculus | |
| 1.4 | - |
Ala-Ala-D-Ala | - |
Oryctolagus cuniculus | |
| 1.4 | - |
L-Ala-Gly-Gly | - |
Oryctolagus cuniculus | |
| 7.5 | - |
Gly-Gly-Gly | - |
Oryctolagus cuniculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Oryctolagus cuniculus | 5737 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | 1 mol per mol of enzyme | Oryctolagus cuniculus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 50000 | 57000 | ultracentrifugation, SDS-PAGE | Oryctolagus cuniculus |
| 57000 | - |
1 * 57000, SDS-PAGE | Oryctolagus cuniculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| side-chain modification | glycoprotein | Oryctolagus cuniculus |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Oryctolagus cuniculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| small intestine mucosa | - |
Oryctolagus cuniculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 380 | - |
- |
Oryctolagus cuniculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Gly-Gly-Gly + H2O | - |
Oryctolagus cuniculus | Gly + Gly-Gly | - |
? | |
| L-Ala-Gly-Gly + H2O | - |
Oryctolagus cuniculus | L-Ala + Gly-Gly | - |
? | |
| L-Ala-L-Ala-D-Ala + H2O | - |
Oryctolagus cuniculus | L-Ala + L-Ala-D-Ala | - |
? | |
| L-Ala-L-Ala-L-Ala + H2O | - |
Oryctolagus cuniculus | L-Ala + L-Ala-L-Ala | - |
? | |
| L-Pro-Gly-Gly + H2O | - |
Oryctolagus cuniculus | L-Pro + Gly-Gly | - |
? | |
| Leu-Gly-Gly + H2O | Leu can be replaced by Ala, Phe, Gly-Pro | Oryctolagus cuniculus | Leu + Gly-Gly | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 57000, SDS-PAGE | Oryctolagus cuniculus |
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Release 2023.1 (January 2023)
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