Activating Compound | Comment | Organism | Structure |
---|---|---|---|
interferon gamma | treating HeLa cells with interferon-gamma increases the amount of ERAP1 | Homo sapiens |
Application | Comment | Organism |
---|---|---|
analysis | two-photon fluorescent probe SNCL exhibits high sensitivity toward ERAP1, with about a 95-fold fluorescence enhancement at 550 nm. SNCL can be applied for monitoring ERAP1 in tumor tissue with an imaging depth of 50-120 microm | Homo sapiens |
medicine | two-photon fluorescent probe SNCL exhibits high sensitivity toward ERAP1, with about a 95-fold fluorescence enhancement at 550 nm. SNCL can be applied for monitoring ERAP1 in tumor tissue with an imaging depth of 50-120 microm | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | the content of ERAP1 is dependent on the redox state of the endoplasmic reticulum | Homo sapiens | 5783 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9NZ08 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-(2-[(4-methylbenzene-1-sulfonyl)amino]ethyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl 2-[(leucylamino)methyl]piperidine-1-carboxylate + H2O | two-photon fluorescent probe SNCL, can be applied for monitoring of the activity in living cells and tissues | Homo sapiens | N-[2-(6-hydroxy-1,3-dioxo-6,6a-dihydro-1H-benzo[de]isoquinolin-2(3H)-yl)ethyl]-4-methylbenzene-1-sulfonamide + hexahydroimidazo[1,5-a]pyridin-3(2H)-one + 2-amino-4-methylpentanoic acid | - |
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