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Literature summary for 3.4.11.22 extracted from

  • Adamis, P.; Mannarino, S.; Riger, C.; Duarte, G.; Cruz, A.; Pereira, M.; Eleutherio, E.
    Lap4, a vacuolar aminopeptidase I, is involved in cadmium-glutathione metabolism (2009), Biometals, 22, 243-249.
    View publication on PubMed
Search for more literature for 3.4.11.22

Localization

Localization Comment Organism GeneOntology No. Textmining
vacuole
-
 Saccharomyces cerevisiae 5773
-

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae BY4741
-
-
-

Synonyms

Synonyms Comment Organism
LAP4
-
 Saccharomyces cerevisiae
vacuolar aminopeptidase I
-
 Saccharomyces cerevisiae

General Information

General Information Comment Organism
malfunction Saccharomyces cerevisiae cells deficient in Lap4 absorb almost 3fold as much cadmium as the wild type strain Saccharomyces cerevisiae
physiological function Lap4 is involved in glutathione degradation, under cadmium stress, Lap4 and gamma-glutamyl transferase work together to assure an efficient glutathione turnover stored in the vacuole Saccharomyces cerevisiae