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Literature summary for 3.4.11.22 extracted from

  • Nagata, H.; Takei, T.; Kojima, R.; Kodera, Y.; Nishimura, H.; Inada, Y.; Matsushima, A.
    Characteristics of an aminopeptidase from Japanese cedar (Cryptomeria japonica) pollen (2005), J. Agric. Food Chem., 53, 5445-5448.
    View publication on PubMed
Search for more literature for 3.4.11.22

Inhibitors

Inhibitors Comment Organism Structure
Co2+
-
 Cryptomeria japonica
Cu2+ noncompetitive Cryptomeria japonica
EDTA
-
 Cryptomeria japonica
additional information no or poor inhibition by Mn2+, Mg2+, and Ca2+ Cryptomeria japonica
Zn2+ competitive Cryptomeria japonica

Metals/Ions

Metals/Ions Comment Organism Structure
additional information the enzyme is a metallopeptidase Cryptomeria japonica

Organism

Organism UniProt Comment Textmining
Cryptomeria japonica
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pollen
-
 Cryptomeria japonica
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.6
-
 substrate L-Phe-L-Phe Cryptomeria japonica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Arg-L-Phe + H2O
-
 Cryptomeria japonica L-Arg + L-Phe
-
 ?
L-Leu-L-Phe + H2O
-
 Cryptomeria japonica L-Leu + L-Phe
-
 ?
L-Met-L-Phe + H2O
-
 Cryptomeria japonica L-Met + L-Phe
-
 ?
L-Phe-7-amido-4-methylcoumarin + H2O
-
 Cryptomeria japonica L-Phe + 7-amino-4-methylcoumarin
-
 ?
L-Phe-L-Ala + H2O
-
 Cryptomeria japonica L-Phe + L-Ala
-
 ?
L-Phe-L-Arg + H2O
-
 Cryptomeria japonica L-Phe + L-Arg
-
 ?
L-Phe-L-Ile + H2O
-
 Cryptomeria japonica L-Phe + L-Ile
-
 ?
L-Phe-L-Leu + H2O
-
 Cryptomeria japonica L-Phe + L-Leu
-
 ?
L-Phe-L-Met + H2O
-
 Cryptomeria japonica L-Phe + L-Met
-
 ?
L-Phe-L-Met-D-Arg-L-Phe-NH2 + H2O
-
 Cryptomeria japonica L-Phe + L-Phe-L-Met-D-Arg-NH2
-
 ?
L-Phe-L-Met-L-Arg-L-Phe-NH2 + H2O bioactive molluscan cardioexcitatory neuropeptide Cryptomeria japonica L-Phe + L-Phe-L-Met-L-Arg-NH2
-
 ?
L-Phe-L-Phe + H2O best substrate Cryptomeria japonica L-Phe + L-Phe
-
 ?
L-Phe-L-Trp + H2O
-
 Cryptomeria japonica L-Phe + L-Trp
-
 ?
L-Phe-L-Tyr + H2O
-
 Cryptomeria japonica L-Phe + L-Tyr
-
 ?
L-Tyr-L-Phe + H2O
-
 Cryptomeria japonica L-Tyr + L-Phe
-
 ?
additional information substrate specificity, overview, no activity with dipeptides D-Phe-D-Phe, Ala-Phe, Asp-Phe, and Pro-Phe, Phe-Gly, Phe-Asp, Phe-Glu, Phe-Val, Phe-Pro, and Phe-Ser, overview Cryptomeria japonica ?
-
 ?

Synonyms

Synonyms Comment Organism
Jc-peptidase
-
 Cryptomeria japonica
LAP
-
 Cryptomeria japonica
leucine aminopeptidase
-
 Cryptomeria japonica

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Cryptomeria japonica

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.3
-
-
 Cryptomeria japonica

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.02
-
 Zn2+ pH 7.5, 37°C Cryptomeria japonica