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Literature summary for 3.4.11.2 extracted from

  • Padia, S.H.; Howell, N.L.; Kemp, B.A.; Fournie-Zaluski, M.C.; Roques, B.P.; Carey, R.M.
    Intrarenal aminopeptidase N inhibition restores defective angiotensin II type 2-mediated natriuresis in spontaneously hypertensive rats (2010), Hypertension, 55, 474-480.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
2-amino-4-methylsulfonyl-butane-thiol selective inhibitor of APN Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Synonyms

Synonyms Comment Organism
aminopeptidase N
-
Rattus norvegicus
APN
-
Rattus norvegicus

General Information

General Information Comment Organism
malfunction amelioration of intrarenal angiotensin II type 2 receptor-mediated natriuresis in prehypertensive spontaneously hypertensive rats is achieved through inhibition of renal APN activity Rattus norvegicus