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Literature summary for 3.4.11.18 extracted from

  • Selvakumar, P.; Lakshmikuttyamma, A.; Lawman, Z.; Bonham, K.; Dimmock, J.R.; Sharma, R.K.
    Expression of methionine aminopeptidase 2,N-myristoyltransferase, and N-myristoyltransferase inhibitor protein 71 in HT29 (2004), Biochem. Biophys. Res. Commun., 322, 1012-1017.
    View publication on PubMed
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Application

Application Comment Organism
medicine in colon cancer cell line HT-29, expression of enzyme is inversely correlated to cell density Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens together with N-myristoyltransferase, enzyme plays a major role in the process of myristoylation of oncoproteins including the c-src family ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
carcinoma cell
-
 Homo sapiens
-
colon colon cancer cell Homo sapiens
-
HT-29 cell colon cancer cell line, expression of enzyme is inversely correlated to cell density Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Met-N-myristoyltransferase + H2O
-
 Homo sapiens L-Met + N-myristoyltransferase
-
 ?
additional information together with N-myristoyltransferase, enzyme plays a major role in the process of myristoylation of oncoproteins including the c-src family Homo sapiens ?
-
 ?