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Literature summary for 3.4.11.15 extracted from

  • Rossier, O.; Dao, J.; Cianciotto, N.P.
    The type II secretion system of Legionella pneumophila elaborates two aminopeptidases, as well as a metalloprotease that contributes to differential infection among protozoan hosts (2008), Appl. Environ. Microbiol., 74, 753-761.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information LapB mutant NU322 (defective for lapB gene) shows a complete loss of lysine aminopeptidase activity and a partial reduction in arginine aminopeptidase activity. When an intact copy of lapB is reintroduced into NU322 aminopeptidase activity is restored Legionella pneumophila

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
Legionella pneumophila
Na+
-
Legionella pneumophila

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35000
-
-
Legionella pneumophila

Organism

Organism UniProt Comment Textmining
Legionella pneumophila
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Arg-2-naphthylamide + H2O
-
Legionella pneumophila Arg + 2-naphthylamine
-
?
Lys-4-nitroanilide + H2O
-
Legionella pneumophila Lys + 4-nitroaniline
-
?

Synonyms

Synonyms Comment Organism
LapB
-
Legionella pneumophila

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Legionella pneumophila

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8
-
assay with Arg-beta-naphthylamide Legionella pneumophila
8
-
assay with Lys-4-nitroanilide Legionella pneumophila