Application | Comment | Organism |
---|---|---|
medicine | production of polyketide antibiotics | Streptomyces hygroscopicus |
synthesis | production of polyketide antibiotics | Streptomyces hygroscopicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | strong inhibition | Streptomyces hygroscopicus | |
amastatin | strong inhibition | Streptomyces hygroscopicus | |
autogenous low molecular weight inhibitor | regulatory function, modulation during periods of intensive polyketide antibiotics formation | Streptomyces hygroscopicus | |
DTT | strong inhibition | Streptomyces hygroscopicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | 2 mol of Zn2+ per mol of enzyme | Streptomyces hygroscopicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
51000 | - |
gel filtration | Streptomyces hygroscopicus |
67000 | - |
1 * 67000, SDS-PAGE | Streptomyces hygroscopicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces hygroscopicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
4573fold | Streptomyces hygroscopicus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
release of an N-terminal amino acid, Xaa-/-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolysed, but rates on arylamides are exceedingly low | prefers leucine and methionine as N-terminal amino acids | Streptomyces hygroscopicus |
Source Tissue | Comment | Organism | Textmining |
---|
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 67000, SDS-PAGE | Streptomyces hygroscopicus |
Synonyms | Comment | Organism |
---|---|---|
leucine aminopeptidase | - |
Streptomyces hygroscopicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
40 | - |
- |
Streptomyces hygroscopicus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
70 | - |
stable up to | Streptomyces hygroscopicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
- |
Streptomyces hygroscopicus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Streptomyces hygroscopicus | - |
- |
8.2 |