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Literature summary for 3.3.2.9 extracted from
- Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function (2018), J. Lipid Res., 59, 684-695 .
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Homo sapiens | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P07099 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the microsomal epoxide hydrolase (EPHX1) is inactive with cis- or trans-allylic epoxides, such as 9R,10R-trans-epoxy-13R-hydroxy-octadeca-11E-enoic acid, 9R,10S-cis-epoxy-13R-hydroxyoctadeca-11E-enoic acid, 12,13-trans-epoxy-octadeca-9E-enoic acid, and 12,13-cis-epoxy-octadeca-9E-enoic acid, in contrast to the soluble epoxide hydrolase, (EPHX2 and EPHX3, EC 3.3.2.10) | Homo sapiens | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| EPHX1 | - |
Homo sapiens |
| mEH | - |
Homo sapiens |
| microsomal EH | - |
Homo sapiens |
| Microsomal epoxide hydrolase | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| additional information | evaluation of different epoxide hydrolase (EH) enzymes in the hydrolysis of skin-relevant fatty acid epoxides and comparison to the products to those of acid-catalyzed hydrolysis | Homo sapiens |
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Release 2023.1 (January 2023)
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