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Literature summary for 3.3.2.9 extracted from

  • Rajapaksa, K.S.; Sipes, I.G.; Hoyer, P.B.
    Involvement of microsomal epoxide hydrolase enzyme in ovotoxicity caused by 7,12-dimethylbenz[a]anthracene (2007), Toxicol. Sci., 96, 327-334.
    View publication on PubMed

Application

Application Comment Organism
medicine incubation of ovaries in a neonatal mouse ovarian culture system in presence of 7,12-dimethylbenz[a]anthracene. At 1 mM 7,12-dimethylbenz[a]anthracene, follicle loss and increased microsomal epoxide hydrolase protein are measured by 6 h. mRNA encoding epoxide hydrolase markedly increases after 2 days of incubation, and this increase precedes accelerated follicle loss at 4 days Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
ovary neonatal mouse ovarian culture system. Incubation of ovaries in presence of 7,12-dimethylbenz[a]anthracene. At 1 mM 7,12-dimethylbenz[a]anthracene, follicle loss and increased microsomal epoxide hydrolase protein are measured by 6 h. mRNA encoding epoxide hydrolase markedly increases after 2 days of incubation, and this increase precedes accelerated follicle loss at 4 days Mus musculus
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