Any feedback?
Literature summary for 3.3.2.9 extracted from
- Molecular properties and biological functions of microsomal epoxide hydrase (1980), Annu. Rev. Pharmacol. Toxicol., 20, 513-531.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Lipid | above the critrical micelle concentration gives kinetic pattern that mimics competitive inhibition | Rattus norvegicus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Homo sapiens | - |
- |
| microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | - |
? | - |
? | |
| additional information | Rattus norvegicus | role in benzopyrene-induced mutagenesis and carcinogenesis | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Homo sapiens | - |
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 7-methylbenzoanthracene + H2O | - |
Rattus norvegicus | ? | - |
? | |
| benzopyrene 4,5-oxide + H2O | - |
Homo sapiens | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| benzopyrene 4,5-oxide + H2O | - |
Rattus norvegicus | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| dibenzoanthracene + H2O | - |
Rattus norvegicus | ? | - |
? | |
| additional information | - |
Homo sapiens | ? | - |
? | |
| additional information | role in benzopyrene-induced mutagenesis and carcinogenesis | Rattus norvegicus | ? | - |
? | |
| octene 1,2-oxide + H2O | - |
Homo sapiens | ? | - |
? | |
| octene 1,2-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
| styrene 7,8-oxide + H2O | - |
Homo sapiens | styrene glycol | - |
? | |
| styrene 7,8-oxide + H2O | - |
Rattus norvegicus | styrene glycol | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
