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Literature summary for 3.3.2.6 extracted from

  • Kadiu, I.; Wang, T.; Schlautman, J.D.; Dubrovsky, L.; Ciborowski, P.; Bukrinsky, M.; Gendelman, H.E.
    HIV-1 transforms the monocyte plasma membrane proteome (2009), Cell. Immunol., 258, 44-58.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Homo sapiens 5829
-
additional information association with the plasma membrane during restricted infection with HIV-1 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
monocyte
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
leukotriene hydrolase A4
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the enzyme is induced by HIV-1 infection, facilitating the protein transformation from the cytosol to the plasma membrane, which is linked to cathepsin B- and caspase 9, 3-dependent apoptosis, overview up

General Information

General Information Comment Organism
additional information HIV-1 transforms the monocyte plasma membrane proteome including also cytosolic LTA4H, the process is linked to cell viability, overview Homo sapiens