Literature summary for 3.3.2.6 extracted from

Gierse, J.K.; Luckow, V.A.; Askonas, L.J.; Duffin, K.L.; Aykent, S.; Bild, G.S.; Rodi, C.P.; Sullivan, P.M.; Bourner, M.J.
High-level expression and purification of human leukotriene A4 hydrolase from insect cells infected with a baculovirus vector (1993), Protein Expr. Purif., 4, 358-366.

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Cloned(Commentary)

Cloned (Comment)	Organism
high-level expression enzyme in Spodoptera frugiperda cells infected with baculovirus vector	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Reaction

Reaction	Comment	Organism	Reaction ID
leukotriene A4 + H2O = leukotriene B4	bifunctional enzyme acting as an epoxide hydrolase and also as an aminopeptidase	Homo sapiens	a

Source Tissue

Source Tissue	Comment	Organism	Textmining
placenta	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
leukotriene A4 + H2O	-	Homo sapiens	leukotriene B4	-	?
additional information	-	Homo sapiens	?	-	?

pI Value

Organism	Comment	pI Value Maximum	pI Value
Homo sapiens	isoform 1	-	5.1
Homo sapiens	isoform 2	-	5.3

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Release 2023.1 (January 2023)