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Literature summary for 3.3.2.2 extracted from
- dentification and characterization of alkenyl hydrolase (lysoplasmalogenase) in microsomes and identification of a plasmalogen-active phospholipase A2 in cytosol of small intestinal epithelium (1999), Biochim. Biophys. Acta, 1437, 142-156.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| deoxycholate | 3.2 mM, 50% inhibition | Rattus norvegicus |  |
| iodoacetate | 12 mM, 17% inhibition | Rattus norvegicus | |
| octyl glucoside | 10 mM, 50% inhibition | Rattus norvegicus | |
| Phenylmethylsulfonylfluoride | 6 mM 29% inhibition; 6 mM, 29% inhibition | Rattus norvegicus | |
| Triton X-100 | 0.09 mM, 50% inhibition | Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | 87% of the activity | Rattus norvegicus | - |
- |
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
| mitochondrion | 14% of the activity | Rattus norvegicus | 5739 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-(1-alkenyl)-sn-glycero-3-phosphocholine + H2O | Rattus norvegicus | - |
aldehyde + sn-glycero-3-phosphocholine | - |
? | |
| 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O | Rattus norvegicus | - |
aldehyde + sn-glycero-3-phosphoethanolamine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| small intestine | epithelium | Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.057 | - |
- |
Rattus norvegicus |
| 0.07 | - |
- |
Rattus norvegicus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, 50% glycerol, stable for more than 12 months | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-(1-alkenyl)-sn-glycero-3-phosphocholine + H2O | - |
Rattus norvegicus | aldehyde + sn-glycero-3-phosphocholine | - |
? | |
| 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O | - |
Rattus norvegicus | aldehyde + sn-glycero-3-phosphoethanolamine | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.8 | 7.4 | - |
Rattus norvegicus |
| 6.8 | 7.4 | substrate 1-(1-alkenyl)-sn-glycero-3-phosphocholine | Rattus norvegicus |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.09 | - |
Triton X-100 | - |
Rattus norvegicus | |
| 10 | - |
octyl glucoside | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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