Literature summary for 3.3.2.10 extracted from

Burmistrov, V.; Morisseau, C.; Harris, T.R.; Butov, G.; Hammock, B.D.
Effects of adamantane alterations on soluble epoxide hydrolase inhibition potency, physical properties and metabolic stability (2018), Bioorg. Chem., 76, 510-527 .

Inhibitors

Inhibitors	Comment	Organism
1-(adamantan-1-yl)-3-(1-propionylpiperidin-4-yl)urea	-	Homo sapiens
1-(adamantan-1-yl)-3-(1-propionylpiperidin-4-yl)urea	-	Mus musculus
1-(adamantan-1-yl)-3-(1-propionylpiperidin-4-yl)urea	-	Rattus norvegicus
1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea	-	Mus musculus
1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea	-	Rattus norvegicus
1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl)urea	-	Homo sapiens
2-[2-(adamantan-1-yl)ethyl]-N-(3,5-dimethyladamantan-1-yl)hydrazine-1-carboxamide	-	Homo sapiens
2-[2-(adamantan-1-yl)ethyl]-N-(3,5-dimethyladamantan-1-yl)hydrazine-1-carboxamide	-	Mus musculus
2-[2-(adamantan-1-yl)ethyl]-N-(3,5-dimethyladamantan-1-yl)hydrazine-1-carboxamide	-	Rattus norvegicus
2-[2-(adamantan-1-yl)ethyl]-N-[(adamantan-1-yl)methyl]hydrazine-1-carboxamide	-	Homo sapiens
2-[2-(adamantan-1-yl)ethyl]-N-[(adamantan-1-yl)methyl]hydrazine-1-carboxamide	-	Mus musculus
2-[2-(adamantan-1-yl)ethyl]-N-[(adamantan-1-yl)methyl]hydrazine-1-carboxamide	-	Rattus norvegicus
2-[3-(adamantan-1-yl)propyl]-N-(3,5-dimethyladamantan-1-yl)hydrazine-1-carboxamide	-	Homo sapiens
2-[3-(adamantan-1-yl)propyl]-N-(3,5-dimethyladamantan-1-yl)hydrazine-1-carboxamide	-	Mus musculus
2-[3-(adamantan-1-yl)propyl]-N-(3,5-dimethyladamantan-1-yl)hydrazine-1-carboxamide	-	Rattus norvegicus
3-([[(adamantan-1-yl)methyl]carbamoyl]amino)adamantan-1-yl trifluoroacetate	-	Homo sapiens
3-([[(adamantan-1-yl)methyl]carbamoyl]amino)adamantan-1-yl trifluoroacetate	-	Mus musculus
3-([[(adamantan-1-yl)methyl]carbamoyl]amino)adamantan-1-yl trifluoroacetate	-	Rattus norvegicus
4-((4-(3-(adamantan-1-yl)ureido)trans-cyclohexyl)oxy)benzoic acid	-	Homo sapiens
4-((4-(3-(adamantan-1-yl)ureido)trans-cyclohexyl)oxy)benzoic acid	-	Mus musculus
4-((4-(3-(adamantan-1-yl)ureido)trans-cyclohexyl)oxy)benzoic acid	-	Rattus norvegicus
4-[(4-[[(3-methyladamantan-1-yl)carbamoyl]amino]cyclohexyl)oxy]benzoic acid	-	Homo sapiens
4-[[(1r,4r)-4-([[(adamantan-1-yl)methyl]carbamoyl]amino)cyclohexyl]oxy]benzoic acid	-	Homo sapiens
4-[[(1r,4r)-4-([[(adamantan-1-yl)methyl]carbamoyl]amino)cyclohexyl]oxy]benzoic acid	-	Mus musculus
4-[[(1r,4r)-4-([[(adamantan-1-yl)methyl]carbamoyl]amino)cyclohexyl]oxy]benzoic acid	-	Rattus norvegicus
4-[[(1r,4r)-4-[[(3,5,7-trimethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Homo sapiens
4-[[(1r,4r)-4-[[(3,5,7-trimethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Mus musculus
4-[[(1r,4r)-4-[[(3,5,7-trimethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Rattus norvegicus
4-[[(1r,4r)-4-[[(3,5-dimethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Homo sapiens
4-[[(1r,4r)-4-[[(3,5-dimethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Mus musculus
4-[[(1r,4r)-4-[[(3,5-dimethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Rattus norvegicus
4-[[(1r,4r)-4-[[(3-chloroadamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Homo sapiens
4-[[(1r,4r)-4-[[(3-chloroadamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Mus musculus
4-[[(1r,4r)-4-[[(3-chloroadamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Rattus norvegicus
4-[[(1r,4r)-4-[[(3-ethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Homo sapiens
4-[[(1r,4r)-4-[[(3-ethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Mus musculus
4-[[(1r,4r)-4-[[(3-ethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Rattus norvegicus
4-[[(1r,4r)-4-[[(3-methyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Homo sapiens
4-[[(1r,4r)-4-[[(3-methyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Mus musculus
4-[[(1r,4r)-4-[[(3-methyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid	-	Rattus norvegicus
4-[[(2R,5R)-5-[[(2-oxoadamantan-1-yl)carbamoyl]amino]piperidin-2-yl]oxy]benzoic acid	-	Homo sapiens
4-[[(2R,5R)-5-[[(2-oxoadamantan-1-yl)carbamoyl]amino]piperidin-2-yl]oxy]benzoic acid	-	Mus musculus
4-[[(2R,5R)-5-[[(2-oxoadamantan-1-yl)carbamoyl]amino]piperidin-2-yl]oxy]benzoic acid	-	Rattus norvegicus
additional information	inhibitory potency and metabolic stability of adamantyl ureas and diureas bearing substituents in bridgehead positions of adamantane and/or spacers between urea groups and adamantane group. Comparison of the effects of the inhibitors on human, rat, and murine enzymes, overview	Homo sapiens
additional information	inhibitory potency and metabolic stability of adamantyl ureas and diureas bearing substituents in bridgehead positions of adamantane and/or spacers between urea groups and adamantane group. Comparison of the effects of the inhibitors on human, rat, and murine enzymes, overview	Mus musculus
additional information	inhibitory potency and metabolic stability of adamantyl ureas and diureas bearing substituents in bridgehead positions of adamantane and/or spacers between urea groups and adamantane group. Comparison of the effects of the inhibitors on human, rat, and murine enzymes, overview	Rattus norvegicus
N,N'-(butane-1,4-diyl)bis[4-(adamantan-2-yl)piperazine-1-carboxamide]	-	Homo sapiens
N,N'-(butane-1,4-diyl)bis[4-(adamantan-2-yl)piperazine-1-carboxamide]	-	Mus musculus
N,N'-(butane-1,4-diyl)bis[4-(adamantan-2-yl)piperazine-1-carboxamide]	-	Rattus norvegicus
N,N'-1,2-phenylenebis[N'-(3-chloroadamantan-1-yl)urea]	-	Homo sapiens
N,N'-1,2-phenylenebis[N'-(3-chloroadamantan-1-yl)urea]	-	Mus musculus
N,N'-1,2-phenylenebis[N'-(3-chloroadamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-1,2-phenylenebis[N'-[(adamantan-1-yl)methyl]urea]	-	Homo sapiens
N,N'-1,2-phenylenebis[N'-[(adamantan-1-yl)methyl]urea]	-	Mus musculus
N,N'-1,2-phenylenebis[N'-[(adamantan-1-yl)methyl]urea]	-	Rattus norvegicus
N,N'-1,4-phenylenebis[N'-[(adamantan-1-yl)methyl]urea]	-	Homo sapiens
N,N'-1,4-phenylenebis[N'-[(adamantan-1-yl)methyl]urea]	-	Mus musculus
N,N'-1,4-phenylenebis[N'-[(adamantan-1-yl)methyl]urea]	-	Rattus norvegicus
N,N'-bis(3,5,7-trimethyladamantan-1-yl)urea	-	Homo sapiens
N,N'-bis(3,5,7-trimethyladamantan-1-yl)urea	-	Mus musculus
N,N'-bis(3,5,7-trimethyladamantan-1-yl)urea	-	Rattus norvegicus
N,N'-bis(3,5-dimethyladamantan-1-yl)urea	-	Homo sapiens
N,N'-bis(3,5-dimethyladamantan-1-yl)urea	-	Mus musculus
N,N'-bis(3,5-dimethyladamantan-1-yl)urea	-	Rattus norvegicus
N,N'-bis(3-chloroadamantan-1-yl)urea	-	Homo sapiens
N,N'-bis(3-chloroadamantan-1-yl)urea	-	Mus musculus
N,N'-bis(3-chloroadamantan-1-yl)urea	-	Rattus norvegicus
N,N'-bis(3-ethyladamantan-1-yl)urea	-	Homo sapiens
N,N'-bis(3-ethyladamantan-1-yl)urea	-	Mus musculus
N,N'-bis(3-ethyladamantan-1-yl)urea	-	Rattus norvegicus
N,N'-bis(3-methyladamantan-1-yl)urea	-	Mus musculus
N,N'-bis(3-methyladamantan-1-yl)urea	-	Rattus norvegicus
N,N'-bis[(adamantan-1-yl)methyl]urea	-	Homo sapiens
N,N'-bis[(adamantan-1-yl)methyl]urea	-	Mus musculus
N,N'-bis[(adamantan-1-yl)methyl]urea	-	Rattus norvegicus
N,N'-butane-1,4-diylbis[N'-(3,5-dimethyladamantan-1-yl)urea]	-	Homo sapiens
N,N'-butane-1,4-diylbis[N'-(3,5-dimethyladamantan-1-yl)urea]	-	Mus musculus
N,N'-butane-1,4-diylbis[N'-(3,5-dimethyladamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-butane-1,4-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Homo sapiens
N,N'-butane-1,4-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Mus musculus
N,N'-butane-1,4-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-butane-1,4-diylbis[N'-(3-ethyladamantan-1-yl)urea]	-	Homo sapiens
N,N'-butane-1,4-diylbis[N'-(3-ethyladamantan-1-yl)urea]	-	Mus musculus
N,N'-butane-1,4-diylbis[N'-(3-ethyladamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-butane-1,4-diylbis[N'-[(3,5-dimethyladamantan-1-yl)methyl]urea]	-	Homo sapiens
N,N'-butane-1,4-diylbis[N'-[(3,5-dimethyladamantan-1-yl)methyl]urea]	-	Mus musculus
N,N'-butane-1,4-diylbis[N'-[(3,5-dimethyladamantan-1-yl)methyl]urea]	-	Rattus norvegicus
N,N'-butane-1,4-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Homo sapiens
N,N'-butane-1,4-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Mus musculus
N,N'-butane-1,4-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Rattus norvegicus
N,N'-butane-1,4-diylbis[N'-[1-(adamantan-1-yl)-2-methylpropan-2-yl]urea]	-	Homo sapiens
N,N'-butane-1,4-diylbis[N'-[1-(adamantan-1-yl)-2-methylpropan-2-yl]urea]	-	Mus musculus
N,N'-butane-1,4-diylbis[N'-[1-(adamantan-1-yl)-2-methylpropan-2-yl]urea]	-	Rattus norvegicus
N,N'-butane-1,4-diylbis[N'-[2-(adamantan-1-yl)-2-phenylethyl]urea]	-	Homo sapiens
N,N'-butane-1,4-diylbis[N'-[2-(adamantan-1-yl)-2-phenylethyl]urea]	-	Mus musculus
N,N'-butane-1,4-diylbis[N'-[2-(adamantan-1-yl)-2-phenylethyl]urea]	-	Rattus norvegicus
N,N'-butane-1,4-diylbis[N'-[2-(adamantan-1-yl)ethyl]urea]	-	Homo sapiens
N,N'-butane-1,4-diylbis[N'-[2-(adamantan-1-yl)ethyl]urea]	-	Mus musculus
N,N'-butane-1,4-diylbis[N'-[2-(adamantan-1-yl)ethyl]urea]	-	Rattus norvegicus
N,N'-butane-1,4-diylbis[N'-[2-(adamantan-1-yl)pentyl]urea]	-	Homo sapiens
N,N'-butane-1,4-diylbis[N'-[2-(adamantan-1-yl)pentyl]urea]	-	Mus musculus
N,N'-butane-1,4-diylbis[N'-[2-(adamantan-1-yl)pentyl]urea]	-	Rattus norvegicus
N,N'-butane-1,4-diylbis[N'-[4-(adamantan-1-yl)phenyl]urea]	-	Homo sapiens
N,N'-butane-1,4-diylbis[N'-[4-(adamantan-1-yl)phenyl]urea]	-	Mus musculus
N,N'-butane-1,4-diylbis[N'-[4-(adamantan-1-yl)phenyl]urea]	-	Rattus norvegicus
N,N'-decane-1,10-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Homo sapiens
N,N'-decane-1,10-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Mus musculus
N,N'-decane-1,10-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-ethane-1,2-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Homo sapiens
N,N'-ethane-1,2-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Mus musculus
N,N'-ethane-1,2-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-ethane-1,2-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Homo sapiens
N,N'-ethane-1,2-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Mus musculus
N,N'-ethane-1,2-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Rattus norvegicus
N,N'-heptane-1,7-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Homo sapiens
N,N'-heptane-1,7-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Mus musculus
N,N'-heptane-1,7-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-heptane-1,7-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Homo sapiens
N,N'-heptane-1,7-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Mus musculus
N,N'-heptane-1,7-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Rattus norvegicus
N,N'-hexane-1,6-diylbis(N'-[3-[(adamantan-1-yl)oxy]propyl]urea)	-	Homo sapiens
N,N'-hexane-1,6-diylbis(N'-[3-[(adamantan-1-yl)oxy]propyl]urea)	-	Mus musculus
N,N'-hexane-1,6-diylbis(N'-[3-[(adamantan-1-yl)oxy]propyl]urea)	-	Rattus norvegicus
N,N'-hexane-1,6-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Homo sapiens
N,N'-hexane-1,6-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Mus musculus
N,N'-hexane-1,6-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-hexane-1,6-diylbis[N'-(3-ethyladamantan-1-yl)urea]	-	Homo sapiens
N,N'-hexane-1,6-diylbis[N'-(3-ethyladamantan-1-yl)urea]	-	Mus musculus
N,N'-hexane-1,6-diylbis[N'-(3-ethyladamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-hexane-1,6-diylbis[N'-[(3,5-dimethyladamantan-1-yl)methyl]urea]	-	Homo sapiens
N,N'-hexane-1,6-diylbis[N'-[(3,5-dimethyladamantan-1-yl)methyl]urea]	-	Mus musculus
N,N'-hexane-1,6-diylbis[N'-[(3,5-dimethyladamantan-1-yl)methyl]urea]	-	Rattus norvegicus
N,N'-hexane-1,6-diylbis[N'-[1-(adamantan-1-yl)ethyl]urea]	-	Homo sapiens
N,N'-hexane-1,6-diylbis[N'-[1-(adamantan-1-yl)ethyl]urea]	-	Mus musculus
N,N'-hexane-1,6-diylbis[N'-[1-(adamantan-1-yl)ethyl]urea]	-	Rattus norvegicus
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)-2-methylpropyl]urea]	-	Homo sapiens
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)-2-methylpropyl]urea]	-	Mus musculus
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)-2-methylpropyl]urea]	-	Rattus norvegicus
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)-2-phenylethyl]urea]	-	Homo sapiens
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)-2-phenylethyl]urea]	-	Mus musculus
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)-2-phenylethyl]urea]	-	Rattus norvegicus
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)butyl]urea]	-	Homo sapiens
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)butyl]urea]	-	Mus musculus
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)butyl]urea]	-	Rattus norvegicus
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)ethyl]urea]	-	Homo sapiens
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)ethyl]urea]	-	Mus musculus
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)ethyl]urea]	-	Rattus norvegicus
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)pentyl]urea]	-	Homo sapiens
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)pentyl]urea]	-	Mus musculus
N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)pentyl]urea]	-	Rattus norvegicus
N,N'-hexane-1,6-diylbis[N'-[4-(adamantan-1-yl)phenyl]urea]	-	Homo sapiens
N,N'-hexane-1,6-diylbis[N'-[4-(adamantan-1-yl)phenyl]urea]	-	Mus musculus
N,N'-hexane-1,6-diylbis[N'-[4-(adamantan-1-yl)phenyl]urea]	-	Rattus norvegicus
N,N'-octane-1,8-diylbis(N'-[3-[(adamantan-1-yl)oxy]propyl]urea)	-	Homo sapiens
N,N'-octane-1,8-diylbis(N'-[3-[(adamantan-1-yl)oxy]propyl]urea)	-	Mus musculus
N,N'-octane-1,8-diylbis(N'-[3-[(adamantan-1-yl)oxy]propyl]urea)	-	Rattus norvegicus
N,N'-octane-1,8-diylbis[N'-(3,5-dimethyladamantan-1-yl)urea]	-	Homo sapiens
N,N'-octane-1,8-diylbis[N'-(3,5-dimethyladamantan-1-yl)urea]	-	Mus musculus
N,N'-octane-1,8-diylbis[N'-(3,5-dimethyladamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-octane-1,8-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Homo sapiens
N,N'-octane-1,8-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Mus musculus
N,N'-octane-1,8-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-octane-1,8-diylbis[N'-[(3,5-dimethyladamantan-1-yl)methyl]urea]	-	Homo sapiens
N,N'-octane-1,8-diylbis[N'-[(3,5-dimethyladamantan-1-yl)methyl]urea]	-	Mus musculus
N,N'-octane-1,8-diylbis[N'-[(3,5-dimethyladamantan-1-yl)methyl]urea]	-	Rattus norvegicus
N,N'-octane-1,8-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Homo sapiens
N,N'-octane-1,8-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Mus musculus
N,N'-octane-1,8-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Rattus norvegicus
N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)-2-methylpropyl]urea]	-	Homo sapiens
N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)-2-methylpropyl]urea]	-	Mus musculus
N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)-2-methylpropyl]urea]	-	Rattus norvegicus
N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)-2-phenylethyl]urea]	-	Homo sapiens
N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)-2-phenylethyl]urea]	-	Mus musculus
N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)-2-phenylethyl]urea]	-	Rattus norvegicus
N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)ethyl]urea]	-	Homo sapiens
N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)ethyl]urea]	-	Mus musculus
N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)ethyl]urea]	-	Rattus norvegicus
N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)pentyl]urea]	-	Homo sapiens
N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)pentyl]urea]	-	Mus musculus
N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)pentyl]urea]	-	Rattus norvegicus
N,N'-octane-1,8-diylbis[N'-[4-(adamantan-1-yl)phenyl]urea]	-	Homo sapiens
N,N'-octane-1,8-diylbis[N'-[4-(adamantan-1-yl)phenyl]urea]	-	Mus musculus
N,N'-octane-1,8-diylbis[N'-[4-(adamantan-1-yl)phenyl]urea]	-	Rattus norvegicus
N,N'-pentane-1,5-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Homo sapiens
N,N'-pentane-1,5-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Mus musculus
N,N'-pentane-1,5-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-pentane-1,5-diylbis[N'-(3-ethyladamantan-1-yl)urea]	-	Homo sapiens
N,N'-pentane-1,5-diylbis[N'-(3-ethyladamantan-1-yl)urea]	-	Mus musculus
N,N'-pentane-1,5-diylbis[N'-(3-ethyladamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-pentane-1,5-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Homo sapiens
N,N'-pentane-1,5-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Mus musculus
N,N'-pentane-1,5-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Rattus norvegicus
N,N'-propane-1,3-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Homo sapiens
N,N'-propane-1,3-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Mus musculus
N,N'-propane-1,3-diylbis[N'-(3-chloroadamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-propane-1,3-diylbis[N'-(3-ethyladamantan-1-yl)urea]	-	Homo sapiens
N,N'-propane-1,3-diylbis[N'-(3-ethyladamantan-1-yl)urea]	-	Mus musculus
N,N'-propane-1,3-diylbis[N'-(3-ethyladamantan-1-yl)urea]	-	Rattus norvegicus
N,N'-propane-1,3-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Homo sapiens
N,N'-propane-1,3-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Mus musculus
N,N'-propane-1,3-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Rattus norvegicus
N,N'-undecane-1,11-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Homo sapiens
N,N'-undecane-1,11-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Mus musculus
N,N'-undecane-1,11-diylbis[N'-[(adamantan-1-yl)methyl]urea]	-	Rattus norvegicus
N,N'-[1,4-phenylenebis(methylene)]bis[N'-(3,5-dimethyladamantan-1-yl)urea]	-	Homo sapiens
N,N'-[1,4-phenylenebis(methylene)]bis[N'-(3,5-dimethyladamantan-1-yl)urea]	-	Mus musculus
N,N'-[1,4-phenylenebis(methylene)]bis[N'-(3,5-dimethyladamantan-1-yl)urea]	-	Rattus norvegicus
N-(2-oxoadamantan-1-yl)-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea	-	Homo sapiens
N-(2-oxoadamantan-1-yl)-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea	-	Mus musculus
N-(2-oxoadamantan-1-yl)-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea	-	Rattus norvegicus
N-(3,5,7-trimethyladamantan-1-yl)-4-([[(3,5,7-trimethyladamantan-1-yl)carbamoyl]amino]methyl)piperidine-1-carboxamide	-	Homo sapiens
N-(3,5,7-trimethyladamantan-1-yl)-4-([[(3,5,7-trimethyladamantan-1-yl)carbamoyl]amino]methyl)piperidine-1-carboxamide	-	Mus musculus
N-(3,5,7-trimethyladamantan-1-yl)-4-([[(3,5,7-trimethyladamantan-1-yl)carbamoyl]amino]methyl)piperidine-1-carboxamide	-	Rattus norvegicus
N-(3,5-dimethyladamantan-1-yl)-N'-(1-propanoylpiperidin-4-yl)urea	-	Homo sapiens
N-(3,5-dimethyladamantan-1-yl)-N'-(1-propanoylpiperidin-4-yl)urea	-	Mus musculus
N-(3,5-dimethyladamantan-1-yl)-N'-(1-propanoylpiperidin-4-yl)urea	-	Rattus norvegicus
N-(3,5-dimethyladamantan-1-yl)-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Homo sapiens
N-(3,5-dimethyladamantan-1-yl)-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Mus musculus
N-(3,5-dimethyladamantan-1-yl)-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Rattus norvegicus
N-(3,5-dimethyladamantan-1-yl)-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea	-	Homo sapiens
N-(3,5-dimethyladamantan-1-yl)-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea	-	Mus musculus
N-(3,5-dimethyladamantan-1-yl)-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea	-	Rattus norvegicus
N-(3,5-dimethyladamantan-1-yl)-N'-[(3-ethyladamantan-1-yl)methyl]urea	-	Homo sapiens
N-(3,5-dimethyladamantan-1-yl)-N'-[(3-ethyladamantan-1-yl)methyl]urea	-	Mus musculus
N-(3,5-dimethyladamantan-1-yl)-N'-[(3-ethyladamantan-1-yl)methyl]urea	-	Rattus norvegicus
N-(3,5-dimethyladamantan-1-yl)-N'-[4-([[(3,5-dimethyladamantan-1-yl)carbamoyl]amino]methyl)phenyl]urea	-	Homo sapiens
N-(3,5-dimethyladamantan-1-yl)-N'-[4-([[(3,5-dimethyladamantan-1-yl)carbamoyl]amino]methyl)phenyl]urea	-	Mus musculus
N-(3,5-dimethyladamantan-1-yl)-N'-[4-([[(3,5-dimethyladamantan-1-yl)carbamoyl]amino]methyl)phenyl]urea	-	Rattus norvegicus
N-(3-ethyladamantan-1-yl)-N'-(1-propanoylpiperidin-4-yl)urea	-	Homo sapiens
N-(3-ethyladamantan-1-yl)-N'-(1-propanoylpiperidin-4-yl)urea	-	Mus musculus
N-(3-ethyladamantan-1-yl)-N'-(1-propanoylpiperidin-4-yl)urea	-	Rattus norvegicus
N-(3-ethyladamantan-1-yl)-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea	-	Mus musculus
N-(3-ethyladamantan-1-yl)-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea	-	Rattus norvegicus
N-adamantan-1-yl-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Homo sapiens
N-adamantan-1-yl-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Mus musculus
N-adamantan-1-yl-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Rattus norvegicus
N-adamantan-1-yl-N'-(3,5-dimethyladamantan-1-yl)urea	-	Homo sapiens
N-adamantan-1-yl-N'-(3,5-dimethyladamantan-1-yl)urea	-	Mus musculus
N-adamantan-1-yl-N'-(3,5-dimethyladamantan-1-yl)urea	-	Rattus norvegicus
N-adamantan-1-yl-N'-[(3-ethyladamantan-1-yl)methyl]urea	-	Homo sapiens
N-adamantan-1-yl-N'-[(3-ethyladamantan-1-yl)methyl]urea	-	Mus musculus
N-adamantan-1-yl-N'-[(3-ethyladamantan-1-yl)methyl]urea	-	Rattus norvegicus
N-[(3,5-dimethyladamantan-1-yl)methyl]-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Homo sapiens
N-[(3,5-dimethyladamantan-1-yl)methyl]-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Mus musculus
N-[(3,5-dimethyladamantan-1-yl)methyl]-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Rattus norvegicus
N-[(3-ethyladamantan-1-yl)methyl]-N'-(1-propanoylpiperidin-4-yl)urea	-	Homo sapiens
N-[(3-ethyladamantan-1-yl)methyl]-N'-(1-propanoylpiperidin-4-yl)urea	-	Mus musculus
N-[(3-ethyladamantan-1-yl)methyl]-N'-(1-propanoylpiperidin-4-yl)urea	-	Rattus norvegicus
N-[(3-ethyladamantan-1-yl)methyl]-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea	-	Homo sapiens
N-[(3-ethyladamantan-1-yl)methyl]-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea	-	Mus musculus
N-[(3-ethyladamantan-1-yl)methyl]-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea	-	Rattus norvegicus
N-[(adamantan-1-yl)methyl]-2-[3-(adamantan-1-yl)propyl]hydrazine-1-carboxamide	-	Homo sapiens
N-[(adamantan-1-yl)methyl]-2-[3-(adamantan-1-yl)propyl]hydrazine-1-carboxamide	-	Mus musculus
N-[(adamantan-1-yl)methyl]-2-[3-(adamantan-1-yl)propyl]hydrazine-1-carboxamide	-	Rattus norvegicus
N-[(adamantan-1-yl)methyl]-4-[([[(adamantan-1-yl)methyl]carbamoyl]amino)methyl]piperidine-1-carboxamide	-	Homo sapiens
N-[(adamantan-1-yl)methyl]-4-[([[(adamantan-1-yl)methyl]carbamoyl]amino)methyl]piperidine-1-carboxamide	-	Mus musculus
N-[(adamantan-1-yl)methyl]-4-[([[(adamantan-1-yl)methyl]carbamoyl]amino)methyl]piperidine-1-carboxamide	-	Rattus norvegicus
N-[(adamantan-1-yl)methyl]-N'-(1-propanoylpiperidin-4-yl)urea	-	Homo sapiens
N-[(adamantan-1-yl)methyl]-N'-(1-propanoylpiperidin-4-yl)urea	-	Mus musculus
N-[(adamantan-1-yl)methyl]-N'-(1-propanoylpiperidin-4-yl)urea	-	Rattus norvegicus
N-[(adamantan-1-yl)methyl]-N'-[2-(adamantan-1-yl)pentyl]urea	-	Homo sapiens
N-[(adamantan-1-yl)methyl]-N'-[2-(adamantan-1-yl)pentyl]urea	-	Mus musculus
N-[(adamantan-1-yl)methyl]-N'-[2-(adamantan-1-yl)pentyl]urea	-	Rattus norvegicus
N-[(adamantan-1-yl)methyl]-N'-[4-(adamantan-1-yl)phenyl]urea	-	Homo sapiens
N-[(adamantan-1-yl)methyl]-N'-[4-(adamantan-1-yl)phenyl]urea	-	Mus musculus
N-[(adamantan-1-yl)methyl]-N'-[4-(adamantan-1-yl)phenyl]urea	-	Rattus norvegicus
N-[1-(adamantan-1-yl)ethyl]-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Homo sapiens
N-[1-(adamantan-1-yl)ethyl]-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Mus musculus
N-[1-(adamantan-1-yl)ethyl]-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Rattus norvegicus
N-[1-(adamantan-1-yl)ethyl]-N'-[(3-ethyladamantan-1-yl)methyl]urea	-	Homo sapiens
N-[1-(adamantan-1-yl)ethyl]-N'-[(3-ethyladamantan-1-yl)methyl]urea	-	Mus musculus
N-[1-(adamantan-1-yl)ethyl]-N'-[(3-ethyladamantan-1-yl)methyl]urea	-	Rattus norvegicus
N-[2-(adamantan-1-yl)butyl]-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Homo sapiens
N-[2-(adamantan-1-yl)butyl]-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Mus musculus
N-[2-(adamantan-1-yl)butyl]-N'-(3,5,7-trimethyladamantan-1-yl)urea	-	Rattus norvegicus
N-[2-(adamantan-1-yl)butyl]-N'-(3,5-dimethyladamantan-1-yl)urea	-	Homo sapiens
N-[2-(adamantan-1-yl)butyl]-N'-(3,5-dimethyladamantan-1-yl)urea	-	Mus musculus
N-[2-(adamantan-1-yl)butyl]-N'-(3,5-dimethyladamantan-1-yl)urea	-	Rattus norvegicus
N-[2-(adamantan-1-yl)ethyl]-N'-[(adamantan-1-yl)methyl]urea	-	Homo sapiens
N-[2-(adamantan-1-yl)ethyl]-N'-[(adamantan-1-yl)methyl]urea	-	Mus musculus
N-[2-(adamantan-1-yl)ethyl]-N'-[(adamantan-1-yl)methyl]urea	-	Rattus norvegicus
N-[2-(adamantan-1-yl)pentyl]-N'-(3-chloroadamantan-1-yl)urea	-	Homo sapiens
N-[2-(adamantan-1-yl)pentyl]-N'-(3-chloroadamantan-1-yl)urea	-	Mus musculus
N-[2-(adamantan-1-yl)pentyl]-N'-(3-chloroadamantan-1-yl)urea	-	Rattus norvegicus
N1,N4-bis[(adamantan-1-yl)methyl]piperazine-1,4-dicarboxamide	-	Homo sapiens
N1,N4-bis[(adamantan-1-yl)methyl]piperazine-1,4-dicarboxamide	-	Mus musculus
N1,N4-bis[(adamantan-1-yl)methyl]piperazine-1,4-dicarboxamide	-	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P34913	-	-
Mus musculus	P34914	-	-
Rattus norvegicus	P80299	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.
cyano(2-methoxynaphthalen-6-yl)methyl trans-(3-phenyloxyran-2-yl)methylcarbonate + H2O	fluorometric activity assay substrate	Homo sapiens	6-methoxy-2-naphthaldehyde + ?	-	?
trans-diphenyl-propene oxide + H2O	-	Mus musculus	trans-diphenyl-propene diol	-	?
trans-diphenyl-propene oxide + H2O	-	Homo sapiens	trans-diphenyl-propene diol	-	?
trans-diphenyl-propene oxide + H2O	-	Rattus norvegicus	trans-diphenyl-propene diol	-	?

Synonyms

Synonyms	Comment	Organism
SEH	-	Mus musculus
SEH	-	Homo sapiens
SEH	-	Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	assay at	Mus musculus
37	-	assay at	Homo sapiens
37	-	assay at	Rattus norvegicus

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.4	-	assay at	Mus musculus
7.4	-	assay at	Homo sapiens
7.4	-	assay at	Rattus norvegicus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor
0.0000004	-	pH 7.4, 37°C	Homo sapiens	3-([[(adamantan-1-yl)methyl]carbamoyl]amino)adamantan-1-yl trifluoroacetate
0.0000004	-	pH 7.4, 37°C	Homo sapiens	N,N'-heptane-1,7-diylbis[N'-[(adamantan-1-yl)methyl]urea]
0.0000004	-	pH 7.4, 37°C	Homo sapiens	N-(2-oxoadamantan-1-yl)-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea
0.0000005	-	pH 7.4, 37°C	Homo sapiens	4-[(4-[[(3-methyladamantan-1-yl)carbamoyl]amino]cyclohexyl)oxy]benzoic acid
0.0000005	-	pH 7.4, 37°C	Homo sapiens	4-[[(1r,4r)-4-[[(3-methyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid
0.0000005	-	pH 7.4, 37°C	Homo sapiens	N,N'-hexane-1,6-diylbis[N'-[1-(adamantan-1-yl)ethyl]urea]
0.0000006	-	pH 7.4, 37°C	Homo sapiens	N,N'-bis(3-chloroadamantan-1-yl)urea
0.0000006	-	pH 7.4, 37°C	Homo sapiens	N,N'-octane-1,8-diylbis[N'-[(adamantan-1-yl)methyl]urea]
0.0000007	-	pH 7.4, 37°C	Homo sapiens	N,N'-butane-1,4-diylbis[N'-[(3,5-dimethyladamantan-1-yl)methyl]urea]
0.0000007	-	pH 7.4, 37°C	Homo sapiens	N,N'-octane-1,8-diylbis[N'-[(adamantan-1-yl)methyl]urea]
0.0000008	-	pH 7.4, 37°C	Homo sapiens	4-[[(1r,4r)-4-[[(3,5-dimethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid
0.0000008	-	pH 7.4, 37°C	Homo sapiens	N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)ethyl]urea]
0.0000008	-	pH 7.4, 37°C	Homo sapiens	N-[(adamantan-1-yl)methyl]-N'-(1-propanoylpiperidin-4-yl)urea
0.0000009	-	pH 7.4, 37°C	Homo sapiens	N,N'-butane-1,4-diylbis[N'-[(adamantan-1-yl)methyl]urea]
0.0000009	-	pH 7.4, 37°C	Homo sapiens	N,N'-decane-1,10-diylbis[N'-(3-chloroadamantan-1-yl)urea]
0.0000009	-	pH 7.4, 37°C	Homo sapiens	N,N'-pentane-1,5-diylbis[N'-[(adamantan-1-yl)methyl]urea]
0.0000009	-	pH 7.4, 37°C	Homo sapiens	N,N'-propane-1,3-diylbis[N'-[(adamantan-1-yl)methyl]urea]
0.000001	-	pH 7.4, 37°C	Homo sapiens	N,N'-hexane-1,6-diylbis[N'-[(3,5-dimethyladamantan-1-yl)methyl]urea]
0.0000011	-	pH 7.4, 37°C	Homo sapiens	N,N'-bis(3,5-dimethyladamantan-1-yl)urea
0.0000011	-	pH 7.4, 37°C	Homo sapiens	N,N'-butane-1,4-diylbis[N'-(3-ethyladamantan-1-yl)urea]
0.0000012	-	pH 7.4, 37°C	Homo sapiens	N,N'-octane-1,8-diylbis[N'-(3-chloroadamantan-1-yl)urea]
0.0000012	-	pH 7.4, 37°C	Homo sapiens	N,N'-pentane-1,5-diylbis[N'-(3-ethyladamantan-1-yl)urea]
0.0000012	-	pH 7.4, 37°C	Homo sapiens	N,N'-undecane-1,11-diylbis[N'-[(adamantan-1-yl)methyl]urea]
0.0000013	-	pH 7.4, 37°C	Homo sapiens	N,N'-butane-1,4-diylbis[N'-(3-chloroadamantan-1-yl)urea]
0.0000014	-	pH 7.4, 37°C	Homo sapiens	4-[[(1r,4r)-4-[[(3-chloroadamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid
0.0000014	-	pH 7.4, 37°C	Homo sapiens	N,N'-heptane-1,7-diylbis[N'-(3-chloroadamantan-1-yl)urea]
0.0000015	-	pH 7.4, 37°C	Homo sapiens	N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)ethyl]urea]
0.0000015	-	pH 7.4, 37°C	Homo sapiens	N-(3,5-dimethyladamantan-1-yl)-N'-[(3-ethyladamantan-1-yl)methyl]urea
0.0000016	-	pH 7.4, 37°C	Homo sapiens	4-[[(1r,4r)-4-([[(adamantan-1-yl)methyl]carbamoyl]amino)cyclohexyl]oxy]benzoic acid
0.0000016	-	pH 7.4, 37°C	Homo sapiens	N,N'-bis(3,5,7-trimethyladamantan-1-yl)urea
0.0000016	-	pH 7.4, 37°C	Homo sapiens	N,N'-hexane-1,6-diylbis[N'-(3-chloroadamantan-1-yl)urea]
0.0000017	-	pH 7.4, 37°C	Homo sapiens	4-[[(1r,4r)-4-[[(3,5,7-trimethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid
0.0000017	-	pH 7.4, 37°C	Homo sapiens	N,N'-propane-1,3-diylbis[N'-(3-chloroadamantan-1-yl)urea]
0.0000017	-	pH 7.4, 37°C	Homo sapiens	N,N'-propane-1,3-diylbis[N'-(3-ethyladamantan-1-yl)urea]
0.0000018	-	pH 7.4, 37°C	Homo sapiens	4-[[(1r,4r)-4-[[(3-ethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid
0.0000018	-	pH 7.4, 37°C	Homo sapiens	N,N'-pentane-1,5-diylbis[N'-(3-chloroadamantan-1-yl)urea]
0.0000018	-	pH 7.4, 37°C	Rattus norvegicus	N-(3,5-dimethyladamantan-1-yl)-N'-(1-propanoylpiperidin-4-yl)urea
0.0000018	-	pH 7.4, 37°C	Homo sapiens	N-[(3-ethyladamantan-1-yl)methyl]-N'-(1-propanoylpiperidin-4-yl)urea
0.0000019	-	pH 7.4, 37°C	Rattus norvegicus	N,N'-bis(3-chloroadamantan-1-yl)urea
0.0000019	-	pH 7.4, 37°C	Homo sapiens	N,N'-butane-1,4-diylbis[N'-[1-(adamantan-1-yl)-2-methylpropan-2-yl]urea]
0.0000019	-	pH 7.4, 37°C	Homo sapiens	N,N'-[1,4-phenylenebis(methylene)]bis[N'-(3,5-dimethyladamantan-1-yl)urea]
0.000002	-	pH 7.4, 37°C	Homo sapiens	4-((4-(3-(adamantan-1-yl)ureido)trans-cyclohexyl)oxy)benzoic acid
0.0000021	-	pH 7.4, 37°C	Mus musculus	N,N'-bis(3-chloroadamantan-1-yl)urea
0.0000024	-	pH 7.4, 37°C	Homo sapiens	N-adamantan-1-yl-N'-[(3-ethyladamantan-1-yl)methyl]urea
0.0000025	-	pH 7.4, 37°C	Homo sapiens	N,N'-octane-1,8-diylbis[N'-[(3,5-dimethyladamantan-1-yl)methyl]urea]
0.0000027	-	pH 7.4, 37°C	Homo sapiens	N,N'-octane-1,8-diylbis(N'-[3-[(adamantan-1-yl)oxy]propyl]urea)
0.0000027	-	pH 7.4, 37°C	Homo sapiens	N-adamantan-1-yl-N'-[(3-ethyladamantan-1-yl)methyl]urea
0.0000028	-	pH 7.4, 37°C	Homo sapiens	N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)butyl]urea]
0.0000028	-	pH 7.4, 37°C	Homo sapiens	N-[(3,5-dimethyladamantan-1-yl)methyl]-N'-(3,5,7-trimethyladamantan-1-yl)urea
0.0000031	-	pH 7.4, 37°C	Rattus norvegicus	N,N'-bis(3-methyladamantan-1-yl)urea
0.0000031	-	pH 7.4, 37°C	Homo sapiens	N-[2-(adamantan-1-yl)pentyl]-N'-(3-chloroadamantan-1-yl)urea
0.0000032	-	pH 7.4, 37°C	Homo sapiens	1-(adamantan-1-yl)-3-(1-propionylpiperidin-4-yl)urea
0.0000033	-	pH 7.4, 37°C	Homo sapiens	N-(3,5-dimethyladamantan-1-yl)-N'-(1-propanoylpiperidin-4-yl)urea
0.0000034	-	pH 7.4, 37°C	Homo sapiens	N,N'-butane-1,4-diylbis[N'-[2-(adamantan-1-yl)ethyl]urea]
0.0000037	-	pH 7.4, 37°C	Homo sapiens	N,N'-octane-1,8-diylbis[N'-(3,5-dimethyladamantan-1-yl)urea]
0.0000037	-	pH 7.4, 37°C	Homo sapiens	1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl)urea
0.0000038	-	pH 7.4, 37°C	Homo sapiens	N-(3-ethyladamantan-1-yl)-N'-(1-propanoylpiperidin-4-yl)urea
0.000004	-	pH 7.4, 37°C	Homo sapiens	N,N'-bis(3-ethyladamantan-1-yl)urea
0.0000043	-	pH 7.4, 37°C	Homo sapiens	N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)-2-methylpropyl]urea]
0.0000044	-	pH 7.4, 37°C	Homo sapiens	N-[2-(adamantan-1-yl)ethyl]-N'-[(adamantan-1-yl)methyl]urea
0.0000045	-	pH 7.4, 37°C	Homo sapiens	4-[[(2R,5R)-5-[[(2-oxoadamantan-1-yl)carbamoyl]amino]piperidin-2-yl]oxy]benzoic acid
0.0000051	-	pH 7.4, 37°C	Rattus norvegicus	N-adamantan-1-yl-N'-(3,5,7-trimethyladamantan-1-yl)urea
0.0000052	-	pH 7.4, 37°C	Mus musculus	N-(3,5-dimethyladamantan-1-yl)-N'-(1-propanoylpiperidin-4-yl)urea
0.0000054	-	pH 7.4, 37°C	Homo sapiens	N,N'-bis[(adamantan-1-yl)methyl]urea
0.0000055	-	pH 7.4, 37°C	Mus musculus	N,N'-bis(3-methyladamantan-1-yl)urea
0.0000061	-	pH 7.4, 37°C	Homo sapiens	N-adamantan-1-yl-N'-(3,5,7-trimethyladamantan-1-yl)urea
0.0000065	-	pH 7.4, 37°C	Homo sapiens	N-(3,5,7-trimethyladamantan-1-yl)-4-([[(3,5,7-trimethyladamantan-1-yl)carbamoyl]amino]methyl)piperidine-1-carboxamide
0.0000067	-	pH 7.4, 37°C	Homo sapiens	N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)-2-methylpropyl]urea]
0.0000085	-	pH 7.4, 37°C	Homo sapiens	N,N'-hexane-1,6-diylbis[N'-(3-ethyladamantan-1-yl)urea]
0.0000094	-	pH 7.4, 37°C	Homo sapiens	N,N'-hexane-1,6-diylbis(N'-[3-[(adamantan-1-yl)oxy]propyl]urea)
0.0000096	-	pH 7.4, 37°C	Homo sapiens	N-adamantan-1-yl-N'-(3,5-dimethyladamantan-1-yl)urea
0.0000122	-	pH 7.4, 37°C	Homo sapiens	N-[(adamantan-1-yl)methyl]-N'-[4-(adamantan-1-yl)phenyl]urea
0.0000128	-	pH 7.4, 37°C	Homo sapiens	N-[1-(adamantan-1-yl)ethyl]-N'-[(3-ethyladamantan-1-yl)methyl]urea
0.0000138	-	pH 7.4, 37°C	Homo sapiens	N-[2-(adamantan-1-yl)butyl]-N'-(3,5-dimethyladamantan-1-yl)urea
0.0000172	-	pH 7.4, 37°C	Homo sapiens	N-[(adamantan-1-yl)methyl]-2-[3-(adamantan-1-yl)propyl]hydrazine-1-carboxamide
0.0000229	-	pH 7.4, 37°C	Homo sapiens	N-[2-(adamantan-1-yl)butyl]-N'-(3,5,7-trimethyladamantan-1-yl)urea
0.0000234	-	pH 7.4, 37°C	Homo sapiens	N,N'-butane-1,4-diylbis[N'-(3,5-dimethyladamantan-1-yl)urea]
0.0000249	-	pH 7.4, 37°C	Rattus norvegicus	N-(3,5,7-trimethyladamantan-1-yl)-4-([[(3,5,7-trimethyladamantan-1-yl)carbamoyl]amino]methyl)piperidine-1-carboxamide
0.0000253	-	pH 7.4, 37°C	Rattus norvegicus	N,N'-bis(3,5,7-trimethyladamantan-1-yl)urea
0.0000254	-	pH 7.4, 37°C	Homo sapiens	N-[1-(adamantan-1-yl)ethyl]-N'-(3,5,7-trimethyladamantan-1-yl)urea
0.0000281	-	pH 7.4, 37°C	Rattus norvegicus	4-[[(1r,4r)-4-[[(3,5,7-trimethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid
0.0000285	-	pH 7.4, 37°C	Homo sapiens	2-[2-(adamantan-1-yl)ethyl]-N-[(adamantan-1-yl)methyl]hydrazine-1-carboxamide
0.0000345	-	pH 7.4, 37°C	Mus musculus	4-[[(1r,4r)-4-[[(3,5,7-trimethyladamantan-1-yl)carbamoyl]amino]cyclohexyl]oxy]benzoic acid
0.0000397	-	pH 7.4, 37°C	Homo sapiens	N-[(adamantan-1-yl)methyl]-4-[([[(adamantan-1-yl)methyl]carbamoyl]amino)methyl]piperidine-1-carboxamide
0.0000606	-	pH 7.4, 37°C	Homo sapiens	N-[(3-ethyladamantan-1-yl)methyl]-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea
0.0000662	-	pH 7.4, 37°C	Mus musculus	N,N'-bis(3,5,7-trimethyladamantan-1-yl)urea
0.0000796	-	pH 7.4, 37°C	Homo sapiens	2-[3-(adamantan-1-yl)propyl]-N-(3,5-dimethyladamantan-1-yl)hydrazine-1-carboxamide
0.0000915	-	pH 7.4, 37°C	Homo sapiens	N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)-2-phenylethyl]urea]
0.0000971	-	pH 7.4, 37°C	Rattus norvegicus	N-(3,5-dimethyladamantan-1-yl)-N'-(3,5,7-trimethyladamantan-1-yl)urea
0.0001069	-	pH 7.4, 37°C	Mus musculus	N-adamantan-1-yl-N'-(3,5,7-trimethyladamantan-1-yl)urea
0.0001199	-	pH 7.4, 37°C	Homo sapiens	2-[2-(adamantan-1-yl)ethyl]-N-(3,5-dimethyladamantan-1-yl)hydrazine-1-carboxamide
0.0001445	-	pH 7.4, 37°C	Homo sapiens	N,N'-ethane-1,2-diylbis[N'-(3-chloroadamantan-1-yl)urea]
0.00016	-	pH 7.4, 37°C	Homo sapiens	N-(3,5-dimethyladamantan-1-yl)-N'-(3,5,7-trimethyladamantan-1-yl)urea
0.0001792	-	pH 7.4, 37°C	Homo sapiens	N,N'-ethane-1,2-diylbis[N'-[(adamantan-1-yl)methyl]urea]
0.000205	-	pH 7.4, 37°C	Homo sapiens	N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)-2-phenylethyl]urea]
0.0002591	-	pH 7.4, 37°C	Homo sapiens	N,N'-octane-1,8-diylbis[N'-[4-(adamantan-1-yl)phenyl]urea]
0.0002686	-	pH 7.4, 37°C	Homo sapiens	N-(3-ethyladamantan-1-yl)-N'-(1-propanoylpiperidin-4-yl)urea
0.0004086	-	pH 7.4, 37°C	Homo sapiens	N,N'-1,2-phenylenebis[N'-(3-chloroadamantan-1-yl)urea]
0.000436	-	pH 7.4, 37°C	Mus musculus	N-(3,5,7-trimethyladamantan-1-yl)-4-([[(3,5,7-trimethyladamantan-1-yl)carbamoyl]amino]methyl)piperidine-1-carboxamide
0.0005293	-	pH 7.4, 37°C	Homo sapiens	N,N'-hexane-1,6-diylbis[N'-[4-(adamantan-1-yl)phenyl]urea]
0.000605	-	pH 7.4, 37°C	Homo sapiens	N,N'-butane-1,4-diylbis[N'-[2-(adamantan-1-yl)-2-phenylethyl]urea]
0.000779	-	pH 7.4, 37°C	Homo sapiens	N,N'-1,4-phenylenebis[N'-[(adamantan-1-yl)methyl]urea]
0.001364	-	pH 7.4, 37°C	Homo sapiens	N,N'-1,2-phenylenebis[N'-[(adamantan-1-yl)methyl]urea]
0.001792	-	pH 7.4, 37°C	Homo sapiens	N,N'-butane-1,4-diylbis[N'-[4-(adamantan-1-yl)phenyl]urea]
0.001992	-	pH 7.4, 37°C	Homo sapiens	N-[(adamantan-1-yl)methyl]-N'-[2-(adamantan-1-yl)pentyl]urea
0.002006	-	pH 7.4, 37°C	Homo sapiens	N1,N4-bis[(adamantan-1-yl)methyl]piperazine-1,4-dicarboxamide
0.002475	-	pH 7.4, 37°C	Homo sapiens	N-(3,5-dimethyladamantan-1-yl)-N'-[4-([[(3,5-dimethyladamantan-1-yl)carbamoyl]amino]methyl)phenyl]urea
0.002894	-	pH 7.4, 37°C	Homo sapiens	N-(3,5-dimethyladamantan-1-yl)-N'-1,3,5-triazatricyclo[3.3.1.13,7]decan-7-ylurea
0.003299	-	pH 7.4, 37°C	Homo sapiens	N,N'-butane-1,4-diylbis[N'-[2-(adamantan-1-yl)pentyl]urea]
0.011376	-	pH 7.4, 37°C	Mus musculus	N-(3,5-dimethyladamantan-1-yl)-N'-(3,5,7-trimethyladamantan-1-yl)urea
0.0168	-	pH 7.4, 37°C	Homo sapiens	N,N'-(butane-1,4-diyl)bis[4-(adamantan-2-yl)piperazine-1-carboxamide]
0.035	-	pH 7.4, 37°C	Homo sapiens	N,N'-hexane-1,6-diylbis[N'-[2-(adamantan-1-yl)pentyl]urea]
0.1	-	pH 7.4, 37°C	Homo sapiens	N,N'-octane-1,8-diylbis[N'-[2-(adamantan-1-yl)pentyl]urea]