Protein Variants | Comment | Organism |
---|---|---|
E254R | the mutant is almost inactive | Homo sapiens |
E254R/R287E | the mutation reduces the enzyme hydrolase activity | Homo sapiens |
R287E | the mutant is almost inactive | Homo sapiens |
R287Q | the mutation reduces the enzyme hydrolase activity | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00584 | - |
Epoxy Fluor 7 | mutant enzyme E254R, at pH 7.4 and 37°C | Homo sapiens | |
0.00691 | - |
Epoxy Fluor 7 | mutant enzyme E254R/R287E, at pH 7.4 and 37°C | Homo sapiens | |
0.00696 | - |
Epoxy Fluor 7 | mutant enzyme R287E, at pH 7.4 and 37°C | Homo sapiens | |
0.01017 | - |
Epoxy Fluor 7 | mutant enzyme R287Q, at pH 7.4 and 37°C | Homo sapiens | |
0.01508 | - |
Epoxy Fluor 7 | wild type enzyme, at pH 7.4 and 37°C | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Homo sapiens | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
80000 | - |
2 * 80000, SDS-PAGE, dimerization is required for enzymatic activity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P34913 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Epoxy Fluor 7 + H2O | i.e. cyano(6-methoxy-2-naphthalenyl)methyl[(2,3)-3-phenyloxiranyl]methyl ester | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | 2 * 80000, SDS-PAGE, dimerization is required for enzymatic activity | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
SEH | - |
Homo sapiens |