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Literature summary for 3.3.2.10 extracted from

  • Manhiani, M.; Quigley, J.E.; Knight, S.F.; Tasoobshirazi, S.; Moore, T.; Brands, M.W.; Hammock, B.D.; Imig, J.D.
    Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension (2009), Am. J. Physiol. Renal Physiol., 297, F740-F748.
    View publication on PubMedView publication on EuropePMC
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Protein Variants

Protein Variants Comment Organism
additional information soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
trans-4[4-(3-adamantanyl-1-yl-ureido)cyclohexyloxy]-benzoic acid i.e.tAUCB Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
 Mus musculus
-
-

Organism

Organism UniProt Comment Textmining
Mus musculus P34914 wild-type and deoxycorticosterone acetate plus high salt, i.e. DOCA-salt, hypertensive mice, gene EPHX2
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Mus musculus
-
macrophage
-
 Mus musculus
-

Synonyms

Synonyms Comment Organism
EPHX2
-
 Mus musculus
SEH
-
 Mus musculus

General Information

General Information Comment Organism
physiological function sEH is responsible for renal protection with DOCA-salt hypertension Mus musculus