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Literature summary for 3.3.2.10 extracted from

  • Enayetallah, A.E.; French, R.A.; Grant, D.F.
    Distribution of soluble epoxide hydrolase, cytochrome P450 2C8, 2C9, and 2J2 in human malignant neoplasms (2006), J. Mol. Histol., 37, 133-141.
    View publication on PubMed

Application

Application Comment Organism
medicine semi-quantitative evaluation of staining intensity of soluble epoxide hydrolase and several cytochromes in different malignant tissues. Soluble epoxide hydrolase expression in renal and hepatic malignant neoplasms and surrounding non-malignant tissues is significantly decreased, whereas expression is increased in seminoma Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
bladder transitional cell carcinoma cell low to high sEH staining Homo sapiens
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breast adenocarcinoma cell line low to moderate sEH staining Homo sapiens
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carcinoma cell different types of malignant neoplasm Homo sapiens
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colonic adenocarcinoma cell low to moderate sEH staining Homo sapiens
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liver cancer cell liver malignant neoplastic tissue and their surrounding non-neoplastic tissues show loss of sEH. Liver cholangiocarcinoma shows significant increase in sEH staining as compared to low or absent staining in corresponding non-neoplastic tissue samples Homo sapiens
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lung adenocarcinoma cell low sEH staining Homo sapiens
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lung squamous cell carcinoma cell
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Homo sapiens
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additional information stomach adenocarcinoma cells with low sEH staining. Skin basal cell carcinoma with low to moderate sEH staining. Testis seminoma with increased sEH expression. Ovary cystadenocarcinoma with low to moderate sEH staining. sEH absent from uterine endometrium. Squamous cell carcinoma of mouth/tongue with low to high sEH staining. Pharynx and larync squamous cell carcinoma with low to moderate sEH staining Homo sapiens
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pancreatic adenocarcinoma cell line no staining in adenocarcinoma cells and islet cell tumors but high staining of matched benigns Homo sapiens
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prostate adenocarcinoma cell low to high sEH staining Homo sapiens
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renal cell carcinoma cell sEH expression in renal malignant neoplasms and surrounding non-neoplastic tissues is significantly decreased Homo sapiens
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Synonyms

Synonyms Comment Organism
More EC 3.3.2.3 Homo sapiens
SEH
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Homo sapiens
soluble epoxide hydrolase
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Homo sapiens