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Literature summary for 3.3.2.10 extracted from

  • Morisseau, C.; Beetham, J.K.; Pinot, F.; Debernard, S.; Newman, J.W.; Hammock, B.D.
    Cress and potato soluble epoxide hydrolases: purification, biochemical characterization, and comparison to mammalian enzymes (2000), Arch. Biochem. Biophys., 378, 321-332.
    View publication on PubMed
Search for more literature for 3.3.2.10

Application

Application Comment Organism
synthesis potential as biocatalyst for the preparation of enantiopure epoxides Solanum tuberosum
synthesis potential as biocatalyst for the preparation of enantiopure epoxides Arabidopsis thaliana

Cloned(Commentary)

Cloned (Comment) Organism
baculovirus expression system Solanum tuberosum
baculovirus expression system cress

Inhibitors

Inhibitors Comment Organism Structure
2,3-epoxy-1,3-diphenyl-propan-1-one IC50: 0.023 mM Arabidopsis thaliana
2,3-epoxy-1,3-diphenyl-propan-1-one IC50: 0.0029 mM Mus musculus
2,3-epoxy-1,3-diphenyl-propan-1-one IC50: 0.0034 mM Solanum tuberosum
2,3-epoxy-1-(4-bromophenyl)-3-phenyl-propan-1-one IC50: 0.013 mM Arabidopsis thaliana
2,3-epoxy-1-(4-bromophenyl)-3-phenyl-propan-1-one IC50: 0.0006 mM Mus musculus
2,3-epoxy-1-(4-bromophenyl)-3-phenyl-propan-1-one IC50: 0.00089 mM Solanum tuberosum
2,3-epoxy-1-(4-ethylphenyl)-3-phenyl-propan-1-one IC50: 0.03 mM Arabidopsis thaliana
2,3-epoxy-1-(4-ethylphenyl)-3-phenyl-propan-1-one IC50: 0.0017 mM Mus musculus
2,3-epoxy-1-(4-ethylphenyl)-3-phenyl-propan-1-one IC50: 0.0014 mM Solanum tuberosum
2,3-epoxy-1-(4-fluorophenyl)-3-phenyl-propan-1-one IC50: 0.022 mM Arabidopsis thaliana
2,3-epoxy-1-(4-fluorophenyl)-3-phenyl-propan-1-one IC50: 0.0018 mM Mus musculus
2,3-epoxy-1-(4-fluorophenyl)-3-phenyl-propan-1-one IC50: 0.0012 mM Solanum tuberosum
2,3-epoxy-1-(4-methoxyphenyl)-3-phenyl-propan-1-one IC50: 0.0054 mM Arabidopsis thaliana
2,3-epoxy-1-(4-methoxyphenyl)-3-phenyl-propan-1-one IC50: 0.00032 mM Mus musculus
2,3-epoxy-1-(4-methoxyphenyl)-3-phenyl-propan-1-one IC50: 0.00021 mM Solanum tuberosum
2,3-epoxy-1-(4-nitroxyphenyl)-3-phenyl-propan-1-one IC50: 0.016 mM Arabidopsis thaliana
2,3-epoxy-1-(4-nitroxyphenyl)-3-phenyl-propan-1-one IC50: 0.0015 mM Mus musculus
2,3-epoxy-1-(4-nitroxyphenyl)-3-phenyl-propan-1-one IC50: 0.019 mM Solanum tuberosum
2,3-epoxy-1-(4-phenylphenyl)-3-phenyl-propan-1-one IC50: 0.00137 mM Mus musculus
2,3-epoxy-1-(4-phenylphenyl)-3-phenyl-propan-1-one IC50: 0.0025 mM Solanum tuberosum
2,3-epoxy-3-(4-bromophenyl)-1-phenyl-propan-1-one IC50: 0.0022 mM Arabidopsis thaliana
2,3-epoxy-3-(4-bromophenyl)-1-phenyl-propan-1-one IC50: 0.0007 mM Mus musculus
2,3-epoxy-3-(4-bromophenyl)-1-phenyl-propan-1-one IC50: 0.00012 mM Solanum tuberosum
2,3-epoxy-3-(4-ethylphenyl)-1-phenyl-propan-1-one IC50: 0.0056 mM Arabidopsis thaliana
2,3-epoxy-3-(4-ethylphenyl)-1-phenyl-propan-1-one IC50: 0.0019 mM Mus musculus
2,3-epoxy-3-(4-ethylphenyl)-1-phenyl-propan-1-one IC50: 0.00016 mM Solanum tuberosum
2,3-epoxy-3-(4-fluorophenyl)-1-phenyl-propan-1-one IC50: 0.0047 mM Arabidopsis thaliana
2,3-epoxy-3-(4-fluorophenyl)-1-phenyl-propan-1-one IC50: 0.0013 mM Mus musculus
2,3-epoxy-3-(4-fluorophenyl)-1-phenyl-propan-1-one IC50: 0.00048 mM Solanum tuberosum
2,3-epoxy-3-(4-methoxyphenyl)-1-phenyl-propan-1-one IC50: 0.0028 mM Arabidopsis thaliana
2,3-epoxy-3-(4-methoxyphenyl)-1-phenyl-propan-1-one IC50: 0.0002 mM Mus musculus
2,3-epoxy-3-(4-methoxyphenyl)-1-phenyl-propan-1-one IC50: 0.00019 mM Solanum tuberosum
2,3-epoxy-3-(4-n-butylphenyl)-1-phenyl-propan-1-one IC50: 0.0017 mM Arabidopsis thaliana
2,3-epoxy-3-(4-n-butylphenyl)-1-phenyl-propan-1-one IC50: 0.00015 mM Mus musculus
2,3-epoxy-3-(4-nitrophenyl)-1-phenyl-propan-1-one IC50: 0.011 mM Arabidopsis thaliana
2,3-epoxy-3-(4-nitrophenyl)-1-phenyl-propan-1-one IC50: 0.00018 mM Mus musculus
2,3-epoxy-3-(4-nitrophenyl)-1-phenyl-propan-1-one IC50: 0.00038 mM Solanum tuberosum
2,3-epoxy-3-(4-phenylphenyl)-1-phenyl-propan-1-one IC50: 0.00014 mM Mus musculus
4-bromo-4'-methoxychalcone IC50: 0.0048 mM Arabidopsis thaliana
4-bromo-4'-methoxychalcone IC50: 0.00027 mM Mus musculus
4-bromo-4'-methoxychalcone IC50: 0.00021 mM Solanum tuberosum
Chalcone oxide
-
 cress
Chalcone oxide
-
 Mus musculus
Chalcone oxide
-
 Solanum tuberosum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Rattus norvegicus
additional information
-
 additional information
-
 Solanum tuberosum
additional information
-
 additional information
-
 cress
0.0043
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Mus musculus
0.0062
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Homo sapiens
0.0069
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Rattus norvegicus
0.007
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Arabidopsis thaliana
0.0083
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Solanum tuberosum

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
 Solanum tuberosum
-
-
soluble
-
 Arabidopsis thaliana
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000
-
 1 * 36000, SDS-PAGE Arabidopsis thaliana
36000
-
 1 * 36000, SDS-PAGE cress
39000
-
 1 * 39000, SDS-PAGE Solanum tuberosum
40000
-
 gel filtration Solanum tuberosum
40000
-
 gel filtration cress
40000
-
 about, gel filtration Solanum tuberosum
40000
-
 about, gel filtration Arabidopsis thaliana
60000
-
 2 * 60000, SDS-PAGE Mus musculus
60000
-
 2 * 60000, SDS-PAGE Homo sapiens
60000
-
 2 * 60000, SDS-PAGE Rattus norvegicus
130000
-
 about, gel filtration Mus musculus
130000
-
 about, gel filtration Homo sapiens
130000
-
 about, gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
 Thale cress
-
cress
-
-
-
Homo sapiens
-
-
-
Mus musculus
-
-
-
Rattus norvegicus
-
-
-
Solanum tuberosum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Solanum tuberosum
-
 Arabidopsis thaliana
-
 cress

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.67
-
-
 Solanum tuberosum
3.9
-
-
 Arabidopsis thaliana
3.91
-
-
 cress

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,3-trans-diphenylpropene oxide + H2O little to no selectivity for cis-isomer or trans-isomer Arabidopsis thaliana 1,3-diphenylpropane-1,2-diol
-
 ?
2,3-epoxy-1,3-diphenyl-propane + H2O
-
 Mus musculus ?
-
 ?
2,3-epoxy-1,3-diphenyl-propane + H2O
-
 Homo sapiens ?
-
 ?
2,3-epoxy-1,3-diphenyl-propane + H2O
-
 Rattus norvegicus ?
-
 ?
2,3-epoxy-1,3-diphenyl-propane + H2O
-
 Solanum tuberosum ?
-
 ?
2,3-epoxy-1,3-diphenyl-propane + H2O
-
 Arabidopsis thaliana ?
-
 ?
4-nitrophenyl (2R,3R)-2,3-epoxy-3-phenylpropyl carbonate + H2O 14.6% of the activity with 2,3-epoxy-1,3-diphenyl-propane, no activity with the 2S,3S-enantiomer Homo sapiens ?
-
 ?
4-nitrophenyl (2R,3R)-2,3-epoxy-3-phenylpropyl carbonate + H2O 5.1% of the activity with 2,3-epoxy-1,3-diphenyl-propane, no activity with the 2S,3S-enantiomer Rattus norvegicus ?
-
 ?
4-nitrophenyl [(2R,3R)-3-phenyloxiran-2-yl]methyl carbonate + H2O 15.2% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana ?
-
 ?
4-nitrophenyl [(2S,3S)-3-phenyloxiran-2-yl]methyl carbonate + H2O 38% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana ?
-
 ?
cis-1,3-diphenylpropene oxide + H2O 2.1% of the activity with 2,3-epoxy-1,3-diphenyl-propane Rattus norvegicus 1,3-diphenylpropane-1,2-diol
-
 ?
cis-1,3-diphenylpropene oxide + H2O little to no selectivity for cis-isomer or trans-isomer, 44% of the activity with 2,3-epoxy-1,3-diphenyl-propane Solanum tuberosum 1,3-diphenylpropane-1,2-diol
-
 ?
cis-1,3-diphenylpropene oxide + H2O little to no selectivity for cis-isomer or trans-isomer, 99% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana 1,3-diphenylpropane-1,2-diol
-
 ?
cis-1,3-diphenylpropene oxide + H2O 18.1% of the activity with 2,3-epoxy-1,3-diphenyl-propane Homo sapiens ?
-
 ?
cis-1,3-diphenylpropene oxide + H2O 3.0% of the activity with 2,3-epoxy-1,3-diphenyl-propane Mus musculus ?
-
 ?
cis-9,10-epoxy-12-octadecenoate methyl ester + H2O 12% of the activity with 2,3-epoxy-1,3-diphenyl-propane Solanum tuberosum 9,10-dihydroxystearic acid methyl ester
-
 ?
cis-9,10-epoxy-12-octadecenoate methyl ester + H2O 3.5% of the activity with 2,3-epoxy-1,3-diphenyl-propane Rattus norvegicus 9,10-dihydroxystearic acid methyl ester
-
 ?
cis-9,10-epoxy-12-octadecenoate methyl ester + H2O 59% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana 9,10-dihydroxystearic acid methyl ester
-
 ?
cis-9,10-epoxy-12-octadecenoate methyl ester + H2O 6.5% of the activity with 2,3-epoxy-1,3-diphenyl-propane Mus musculus 9,10-dihydroxystearic acid methyl ester
-
 ?
cis-9,10-epoxy-12-octadecenoate methyl ester + H2O 5.2% of the activity with 2,3-epoxy-1,3-diphenyl-propane Homo sapiens ?
-
 ?
cis-9,10-epoxystearic acid + H2O 13.4% of the activity with 2,3-epoxy-1,3-diphenyl-propane Solanum tuberosum 9,10-dihydroxystearic acid
-
 ?
cis-9,10-epoxystearic acid + H2O 30% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana 9,10-dihydroxystearic acid
-
 ?
cis-9,10-epoxystearic acid + H2O 4.1% of the activity with 2,3-epoxy-1,3-diphenyl-propane Rattus norvegicus 9,10-dihydroxystearic acid
-
 ?
cis-9,10-epoxystearic acid + H2O 6.7% of the activity with 2,3-epoxy-1,3-diphenyl-propane Mus musculus 9,10-dihydroxystearic acid
-
 ?
cis-9,10-epoxystearic acid + H2O 7.9% of the activity with 2,3-epoxy-1,3-diphenyl-propane Homo sapiens ?
-
 ?
cis-stilbene oxide + H2O
-
 Mus musculus ?
-
 ?
cis-stilbene oxide + H2O
-
 Homo sapiens ?
-
 ?
cis-stilbene oxide + H2O
-
 Rattus norvegicus ?
-
 ?
cis-stilbene oxide + H2O greater selectivity for trans-stilbene oxide versus cis-stilbene oxide Solanum tuberosum ?
-
 ?
cis-stilbene oxide + H2O greater selectivity for trans-stilbene oxide versus cis-stilbene oxide cress ?
-
 ?
cis-stilbene oxide + H2O 0.4% of the activity with 2,3-epoxy-1,3-diphenyl-propane Mus musculus 1,2-diphenylethane-1,2-diol
-
 ?
cis-stilbene oxide + H2O far greater selectivity for trans-stilbene oxide versus cis-stilbene oxide. 0.06% of the activity with 2,3-epoxy-1,3-diphenyl-propane Solanum tuberosum 1,2-diphenylethane-1,2-diol
-
 ?
cis-stilbene oxide + H2O far greater selectivity for trans-stilbene oxide versus cis-stilbene oxide. 0.2% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana 1,2-diphenylethane-1,2-diol
-
 ?
juvenile hormone III + H2O 11.9% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana ?
-
 ?
juvenile hormone III + H2O 3.5% of the activity with 2,3-epoxy-1,3-diphenyl-propane Rattus norvegicus ?
-
 ?
juvenile hormone III + H2O 6.3% of the activity with 2,3-epoxy-1,3-diphenyl-propane Mus musculus ?
-
 ?
juvenile hormone III + H2O 6.3% of the activity with 2,3-epoxy-1,3-diphenyl-propane Homo sapiens ?
-
 ?
juvenile hormone III + H2O 7.1% of the activity with 2,3-epoxy-1,3-diphenyl-propane Solanum tuberosum ?
-
 ?
trans-1,3-diphenylpropene oxide + H2O
-
 Solanum tuberosum ?
-
 ?
trans-1,3-diphenylpropene oxide + H2O
-
 cress ?
-
 ?
trans-1,3-diphenylpropene oxide + H2O little to no selectivity for cis-isomer or trans-isomer Solanum tuberosum 1,3-diphenylpropane-1,2-diol
-
 ?
trans-stilbene oxide + H2O
-
 Mus musculus ?
-
 ?
trans-stilbene oxide + H2O
-
 Homo sapiens ?
-
 ?
trans-stilbene oxide + H2O
-
 Rattus norvegicus ?
-
 ?
trans-stilbene oxide + H2O greater selectivity for trans-stilbene oxide versus cis-stilbene oxide Solanum tuberosum ?
-
 ?
trans-stilbene oxide + H2O greater selectivity for trans-stilbene oxide versus cis-stilbene oxide cress ?
-
 ?
trans-stilbene oxide + H2O highly selective for the trans-enantiomer. 1.2% of the activity with 2,3-epoxy-1,3-diphenyl-propane Homo sapiens ?
-
 ?
trans-stilbene oxide + H2O 2.8% of the activity with 2,3-epoxy-1,3-diphenyl-propane Mus musculus 1,2-diphenylethane-1,2-diol
-
 ?
trans-stilbene oxide + H2O far greater selectivity for trans-stilbene oxide versus cis-stilbene oxide. 5.6% of the activity with 2,3-epoxy-1,3-diphenyl-propane Solanum tuberosum 1,2-diphenylethane-1,2-diol
-
 ?
trans-stilbene oxide + H2O far greater selectivity for trans-stilbene oxide versus cis-stilbene oxide. 84% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana 1,2-diphenylethane-1,2-diol
-
 ?
trans-stilbene oxide + H2O highly selective for the trans-enantiomer. 1% of the activity with 2,3-epoxy-1,3-diphenyl-propane Rattus norvegicus 1,2-diphenylethane-1,2-diol
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 60000, SDS-PAGE Mus musculus
dimer 2 * 60000, SDS-PAGE Homo sapiens
dimer 2 * 60000, SDS-PAGE Rattus norvegicus
monomer
-
 Mus musculus
monomer
-
 Homo sapiens
monomer 1 * 39000, SDS-PAGE Solanum tuberosum
monomer 1 * 36000, SDS-PAGE Arabidopsis thaliana
monomer 1 * 36000, SDS-PAGE cress

Synonyms

Synonyms Comment Organism
PsEH
-
 Solanum tuberosum

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
30
-
 t1/2 is 17.4 h Mus musculus
30
-
 t1/2: 20.3 h Rattus norvegicus
30
-
 t1/2: 8.1 h Homo sapiens
37
-
-
 Solanum tuberosum
37
-
 t1/2: more than 24 h cress
37
-
 t1/2: 2.0 h Rattus norvegicus
37
-
 t1/2: 18 h Mus musculus
37
-
 t1/2: 1.3 h Homo sapiens
37
-
 t1/2: 2 h Rattus norvegicus
37
-
 t1/2 is 1.8 h Mus musculus
45
-
 t1/2 is 10.2 h Arabidopsis thaliana
51
-
 t1/2: more than 24 h Solanum tuberosum
51
-
 t1/2: 6.4 h cress
51
-
 t1/2 is 6.4 h Arabidopsis thaliana
55
-
 t1/2: 0.93 h cress
55
-
 t1/2: 4.7 h Solanum tuberosum
55
-
 t1/2 is 0.93 h Arabidopsis thaliana
55
-
 t1/2 is 4.7 h Solanum tuberosum
59
-
 t1/2: 0.38 h cress
59
-
 t1/2: 0.87 h Solanum tuberosum
59
-
 t1/2 is 0.38 h Arabidopsis thaliana
59
-
 t1/2 is 0.87 h Solanum tuberosum

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Solanum tuberosum
additional information
-
 additional information
-
 cress
1.64
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Arabidopsis thaliana
4.3
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Homo sapiens
4.76
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Solanum tuberosum
12
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Rattus norvegicus
18
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Mus musculus

pI Value

Organism Comment pI Value Maximum pI Value
Arabidopsis thaliana electrofocusing, pH-gradient 3.0-7.0
-
 4.5
Solanum tuberosum electrofocusing, pH-gradient 3.0-7.0
-
 5
Mus musculus electrofocusing, pH-gradient 3.0-7.0
-
 5.5
Homo sapiens electrofocusing, pH-gradient 3.0-7.0
-
 5.5
Rattus norvegicus electrofocusing, pH-gradient 3.0-7.0
-
 5.5

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00012
-
 IC50: 0.00012 mM Solanum tuberosum 2,3-epoxy-3-(4-bromophenyl)-1-phenyl-propan-1-one
0.00014
-
 IC50: 0.00014 mM Mus musculus 2,3-epoxy-3-(4-phenylphenyl)-1-phenyl-propan-1-one
0.00015
-
 IC50: 0.00015 mM Mus musculus 2,3-epoxy-3-(4-n-butylphenyl)-1-phenyl-propan-1-one
0.00016
-
 IC50: 0.00016 mM Solanum tuberosum 2,3-epoxy-3-(4-ethylphenyl)-1-phenyl-propan-1-one
0.00018
-
 IC50: 0.00018 mM Mus musculus 2,3-epoxy-3-(4-nitrophenyl)-1-phenyl-propan-1-one
0.00019
-
 IC50: 0.00019 mM Solanum tuberosum 2,3-epoxy-3-(4-methoxyphenyl)-1-phenyl-propan-1-one
0.0002
-
 IC50: 0.0002 mM Mus musculus 2,3-epoxy-3-(4-methoxyphenyl)-1-phenyl-propan-1-one
0.00021
-
 IC50: 0.00021 mM Solanum tuberosum 2,3-epoxy-1-(4-methoxyphenyl)-3-phenyl-propan-1-one
0.00021
-
 IC50: 0.00021 mM Solanum tuberosum 4-bromo-4'-methoxychalcone
0.00027
-
 IC50: 0.00027 mM Mus musculus 4-bromo-4'-methoxychalcone
0.00032
-
 IC50: 0.00032 mM Mus musculus 2,3-epoxy-1-(4-methoxyphenyl)-3-phenyl-propan-1-one
0.00038
-
 IC50: 0.00038 mM Solanum tuberosum 2,3-epoxy-3-(4-nitrophenyl)-1-phenyl-propan-1-one
0.00048
-
 IC50: 0.00048 mM Solanum tuberosum 2,3-epoxy-3-(4-fluorophenyl)-1-phenyl-propan-1-one
0.0006
-
 IC50: 0.0006 mM Mus musculus 2,3-epoxy-1-(4-bromophenyl)-3-phenyl-propan-1-one
0.0007
-
 IC50: 0.0007 mM Mus musculus 2,3-epoxy-3-(4-bromophenyl)-1-phenyl-propan-1-one
0.00089
-
 IC50: 0.00089 mM Solanum tuberosum 2,3-epoxy-1-(4-bromophenyl)-3-phenyl-propan-1-one
0.0012
-
 IC50: 0.0012 mM Solanum tuberosum 2,3-epoxy-1-(4-fluorophenyl)-3-phenyl-propan-1-one
0.0013
-
 IC50: 0.0013 mM Mus musculus 2,3-epoxy-3-(4-fluorophenyl)-1-phenyl-propan-1-one
0.00137
-
 IC50: 0.00137 mM Mus musculus 2,3-epoxy-1-(4-phenylphenyl)-3-phenyl-propan-1-one
0.0014
-
 IC50: 0.0014 mM Solanum tuberosum 2,3-epoxy-1-(4-ethylphenyl)-3-phenyl-propan-1-one
0.0015
-
 IC50: 0.0015 mM Mus musculus 2,3-epoxy-1-(4-nitroxyphenyl)-3-phenyl-propan-1-one
0.0017
-
 IC50: 0.0017 mM Mus musculus 2,3-epoxy-1-(4-ethylphenyl)-3-phenyl-propan-1-one
0.0017
-
 IC50: 0.0017 mM Arabidopsis thaliana 2,3-epoxy-3-(4-n-butylphenyl)-1-phenyl-propan-1-one
0.0018
-
 IC50: 0.0018 mM Mus musculus 2,3-epoxy-1-(4-fluorophenyl)-3-phenyl-propan-1-one
0.0019
-
 IC50: 0.0019 mM Mus musculus 2,3-epoxy-3-(4-ethylphenyl)-1-phenyl-propan-1-one
0.0022
-
 IC50: 0.0022 mM Arabidopsis thaliana 2,3-epoxy-3-(4-bromophenyl)-1-phenyl-propan-1-one
0.0025
-
 IC50: 0.0025 mM Solanum tuberosum 2,3-epoxy-1-(4-phenylphenyl)-3-phenyl-propan-1-one
0.0028
-
 IC50: 0.0028 mM Arabidopsis thaliana 2,3-epoxy-3-(4-methoxyphenyl)-1-phenyl-propan-1-one
0.0029
-
 IC50: 0.0029 mM Mus musculus 2,3-epoxy-1,3-diphenyl-propan-1-one
0.0034
-
 IC50: 0.0034 mM Solanum tuberosum 2,3-epoxy-1,3-diphenyl-propan-1-one
0.0047
-
 IC50: 0.0047 mM Arabidopsis thaliana 2,3-epoxy-3-(4-fluorophenyl)-1-phenyl-propan-1-one
0.0048
-
 IC50: 0.0048 mM Arabidopsis thaliana 4-bromo-4'-methoxychalcone
0.0054
-
 IC50: 0.0054 mM Arabidopsis thaliana 2,3-epoxy-1-(4-methoxyphenyl)-3-phenyl-propan-1-one
0.0056
-
 IC50: 0.0056 mM Arabidopsis thaliana 2,3-epoxy-3-(4-ethylphenyl)-1-phenyl-propan-1-one
0.011
-
 IC50: 0.011 mM Arabidopsis thaliana 2,3-epoxy-3-(4-nitrophenyl)-1-phenyl-propan-1-one
0.013
-
 IC50: 0.013 mM Arabidopsis thaliana 2,3-epoxy-1-(4-bromophenyl)-3-phenyl-propan-1-one
0.016
-
 IC50: 0.016 mM Arabidopsis thaliana 2,3-epoxy-1-(4-nitroxyphenyl)-3-phenyl-propan-1-one
0.019
-
 IC50: 0.019 mM Solanum tuberosum 2,3-epoxy-1-(4-nitroxyphenyl)-3-phenyl-propan-1-one
0.022
-
 IC50: 0.022 mM Arabidopsis thaliana 2,3-epoxy-1-(4-fluorophenyl)-3-phenyl-propan-1-one
0.023
-
 IC50: 0.023 mM Arabidopsis thaliana 2,3-epoxy-1,3-diphenyl-propan-1-one
0.03
-
 IC50: 0.03 mM Arabidopsis thaliana 2,3-epoxy-1-(4-ethylphenyl)-3-phenyl-propan-1-one