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Literature summary for 3.2.2.6 extracted from

  • Broeker, M.; Schindelmeiser, J.; Pape, H.
    A nicotinamide adenine dinucleotide (phosphate) glycohydrolase [NAD(P)ase, EC 3.2.2.6] from Streptomyces griseus (1979), FEMS Microbiol. Lett., 6, 245-247.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
HClO4 5%, 2°C, 10 min, 60% loss of the original activity Streptomyces griseus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.65
-
NADP+
-
Streptomyces griseus
1.33
-
NAD+
-
Streptomyces griseus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1600000
-
gel filtration Streptomyces griseus

Organism

Organism UniProt Comment Textmining
Streptomyces griseus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Streptomyces griseus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NAD+ + H2O
-
Streptomyces griseus ADP-D-ribose + nicotinamide
-
?
NADP+ + H2O
-
Streptomyces griseus nicotinamide + ADPribose-phosphate
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
56
-
-
Streptomyces griseus

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
60
-
rapid loss of activity above Streptomyces griseus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.5 8
-
Streptomyces griseus