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Literature summary for 3.2.2.5 extracted from

  • Minami, M.; Kamimura, T.; Isaka, M.; Tatsuno, I.; Ohta, M.; Hasegawa, T.
    Clindamycin-induced CovS-mediated regulation of the production of virulent exoproteins streptolysin O, NAD glycohydrolase, and streptokinase in Streptococcus pyogenes (2010), Antimicrob. Agents Chemother., 54, 98-102.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Streptococcus pyogenes
-
 M1 serotype clindamycin CLI-resistant D2TY
-

Synonyms

Synonyms Comment Organism
NAD glycohydrolase
-
 Streptococcus pyogenes
Nga
-
 Streptococcus pyogenes

Expression

Organism Comment Expression
Streptococcus pyogenes clindamycin, CLI, induces the expression of Nga, and of the other two major toxins, streptolysin O and streptokinase, in the streptococcal toxic shock syndrome, in CLI-resistant isogenic covS mutant D2TYcovS strain, overview up

General Information

General Information Comment Organism
malfunction the enzyme represents one major virulent exoprotein in the streptococcal toxic shock syndrome, overview Streptococcus pyogenes