Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.2.2.31 extracted from

  • Wang, L.; Lee, S.J.; Verdine, G.L.
    Structural basis for avoidance of promutagenic DNA repair by MutY adenine DNA glycosylase (2015), J. Biol. Chem., 290, 17096-17105 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.2.31

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with DNA, hanging drop vapor diffusion method, using 100 mM Tris, pH 8.0, 250 mM NaOAc, 29% (w/v) PEG 4000 Geobacillus stearothermophilus

Protein Variants

Protein Variants Comment Organism
D144N active site mutant Geobacillus stearothermophilus
P164C active site mutant Geobacillus stearothermophilus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA containing an adenine:8-oxoguanine mismatch + H2O Geobacillus stearothermophilus
-
 ?
-
 ?
additional information Geobacillus stearothermophilus no activity with DNA containing a cytosine:8-oxoguanine mismatch ?
-
 ?

Organism

Organism UniProt Comment Textmining
Geobacillus stearothermophilus P83847
-
-

Purification (Commentary)

Purification (Comment) Organism
MonoQ column chromatography Geobacillus stearothermophilus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA containing an adenine:8-oxoguanine mismatch + H2O
-
 Geobacillus stearothermophilus ?
-
 ?
additional information no activity with DNA containing a cytosine:8-oxoguanine mismatch Geobacillus stearothermophilus ?
-
 ?

Synonyms

Synonyms Comment Organism
mutY
-
 Geobacillus stearothermophilus