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Literature summary for 3.2.2.31 extracted from

  • Chmiel, N.H.; Golinelli, M.P.; Francis, A.W.; David, S.S.
    Efficient recognition of substrates and substrate analogs by the adenine glycosylase MutY requires the C-terminal domain (2001), Nucleic Acids Res., 29, 553-564 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.2.31

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli JM101 cells Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA containing a 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine mismatch + H2O Escherichia coli highest activity ?
-
 ?
DNA containing a guanine:adenine mismatch + H2O Escherichia coli
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
heparin-Sepharose column chromatography Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA containing a 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine mismatch + H2O highest activity Escherichia coli ?
-
 ?
DNA containing a guanine:adenine mismatch + H2O
-
 Escherichia coli ?
-
 ?
additional information no activity with DNA containing tetrahydrofuran nucleotide, 2'-deoxyformycin, 2'-deoxy-2'-fluoroadenosine, 4-methylindole beta-deoxynucleoside, purine 2'-deoxynucleoside, and 2'-deoxycytifinde opposite either guanine or 7,8-dihydro-8-oxo-2'-deoxyguanosine Escherichia coli ?
-
 ?

Synonyms

Synonyms Comment Organism
adenine glycosylase
-
 Escherichia coli
mutY
-
 Escherichia coli