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Literature summary for 3.2.2.31 extracted from
- A substrate recognition role for the [4Fe-4S]2+ cluster of the DNA repair glycosylase MutY (1998), Biochemistry, 37, 6465-6475 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| mutY | - |
Escherichia coli |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| [4Fe-4S]-center | the [4Fe-4S]2+ cluster is critical for the specific recognition of substrate DNA necessary for the adenine glycosylase activity of the enzyme | Escherichia coli |  |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme prevents mutations due to misincorporation of adenine opposite 7,8-dihydro-8-oxo-2'-deoxyguanosine during DNA replication by removing the adenine base | Escherichia coli |
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