Crystallization (Comment) | Organism |
---|---|
structures of wild-type cocrystallized with S-adenosylhomocysteine, formycin A, and (3R,4S)-4-(4-chlorophenylthiomethyl)-1-[(9-deazaadenin-9-yl)methyl]-3-hydroxypyrrolidine as well as one structure of inactive variant D198N cocrystallized with S-adenosylhomocysteine. Mechanism of D198 pKa elevation is through the sharing of a proton with atom N7 of the adenine moiety possessing unconventional hydrogen-bond geometry | Helicobacter pylori |
Protein Variants | Comment | Organism |
---|---|---|
D198N | inactive | Helicobacter pylori |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Helicobacter pylori | Q9ZMY2 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-amino-6-deoxyfutalosine + H2O | - |
Helicobacter pylori | dehypoxanthine futalosine + adenine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MTAN | - |
Helicobacter pylori |
MtnN | - |
Helicobacter pylori |