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Literature summary for 3.2.2.27 extracted from
- The Simian varicella virus uracil DNA glycosylase and dUTPase genes are expressed in vivo, but are non-essential for replication in cell culture (2009), Virus Res., 142, 78-84.
Application
| Application | Comment | Organism |
|---|---|---|
| additional information | the UDG mutant ight be useful as a varicella vaccine | Cercopithecine alphaherpesvirus 9 |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| UDG DNA sequence determination and analysis | Cercopithecine alphaherpesvirus 9 |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | construction of infectious SVV mutants defective in either dUTPase or UDG activity or both using recA assisted restriction endonuclease cleavage and a cosmid recombination system. The mutant lose their viral dUTPase and UDG enzymatic activity in infected CV-1 cells | Cercopithecine alphaherpesvirus 9 |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cercopithecine alphaherpesvirus 9 | - |
SVV | - |
| Cercopithecine alphaherpesvirus 9 SVV | - |
SVV | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | enzyme substrate is uracil-labeled calf thymus DNA prepared by nick translation with dUTP | Cercopithecine alphaherpesvirus 9 | ? | - |
? |  |
| additional information | enzyme substrate is uracil-labeled calf thymus DNA prepared by nick translation with dUTP | Cercopithecine alphaherpesvirus 9 SVV | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| UDG | - |
Cercopithecine alphaherpesvirus 9 |
| uracil DNA glycosylase | - |
Cercopithecine alphaherpesvirus 9 |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Cercopithecine alphaherpesvirus 9 |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
assay at | Cercopithecine alphaherpesvirus 9 |
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Release 2023.1 (January 2023)
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