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Literature summary for 3.2.2.22 extracted from

  • Guo, Q.; Zhou, W.; Too, H.M.; Li, J.; Liu, Y.; Bartlam, M.; Dong, Y.; Wong, K.B.; Shaw, P.C.; Rao, Z.
    Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants (2003), Protein Eng., 16, 391-396.
    View publication on PubMed
Search for more literature for 3.2.2.22

Application

Application Comment Organism
medicine
-
 Trichosanthes sp.

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structures of several E85 mutant TCS complexes with adenosine-5'-monophosphate, E85A, space group P2(1)2(1)2(1), unit cell constants a = 38.3, b = 76.7, c= 79.2 Trichosanthes sp.
E85Q, space group P2(1)2(1)2(1), unit cell constants a = 38.0, b = 75.9, c= 78.4 Trichosanthes sp.
E85R, space group P2(1)2(1)2(1), unit cell constants a = 38.0, b = 75.3, c= 78.4 Trichosanthes sp.

Protein Variants

Protein Variants Comment Organism
E85A site-directed mutagenesis Trichosanthes sp.
E85Q site-directed mutagenesis Trichosanthes sp.
E85R site-directed mutagenesis Trichosanthes sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
rRNA + H2O Trichosanthes sp.
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Trichosanthes sp.
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
rRNA + H2O
-
 Trichosanthes sp. ?
-
 ?

Synonyms

Synonyms Comment Organism
trichosanthin
-
 Trichosanthes sp.