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Literature summary for 3.2.2.22 extracted from

  • Endo, Y.; Tsurugi, K.
    The RNA N-glycosidase activity of ricin A-chain (1988), Nucleic Acids Symp. Ser., 19, 139-142.
    View publication on PubMed
Search for more literature for 3.2.2.22

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0026
-
 rRNA pH 7.6, 37°C, rat liver 80S ribosome Ricinus communis
0.0058
-
 rRNA pH 7.6, 37°C, rat liver naked 28 S rRNA Ricinus communis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
rRNA + H2O Ricinus communis
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Ricinus communis
-
 castor bean
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
rRNA + H2O
-
 Ricinus communis ?
-
 ?
rRNA + H2O with deproteinized Escherichia coli rRNA as substrate, ricin A-chain cleaves the N-glycosidic bond at A-2600 in 23S rRNA Ricinus communis ?
-
 ?
rRNA + H2O cleaves the N-glycosidic bond and removes adenine at A-4324 in 28 S rRNA when intact rat ribosomes are the substrate, cleaves the same N-glycosidic bond in naked 28 S rRNA Ricinus communis ?
-
 ?
rRNA + H2O rat liver 28 S rRNA Ricinus communis ?
-
 ?

Synonyms

Synonyms Comment Organism
ricin A-chain
-
 Ricinus communis

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
29.6
-
 rRNA
-
 Ricinus communis