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Literature summary for 3.2.2.20 extracted from
- Effect of overexpression of E. coli 3-methyladenine-DNA glycosylase I (Tag) on survival and mutation induction in Salmonella typhimurium (1996), Mutat. Res., 358, 81-87.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| cloned and overexpressed in Salmonella typhimurium | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alkylated DNA + H2O | Escherichia coli | primarily removes N3-methyladenine but also N3-methylguanine from DNA by glycosylic cleavage in the first step of the base excision repair | 3-methyladenine + ? | - |
? |  |
| alkylated DNA + H2O | Escherichia coli | constititively expressed | 3-methyladenine + ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alkylated DNA + H2O | calf thymus DNA | Escherichia coli | 3-methyladenine + ? | - |
? | |
| alkylated DNA + H2O | primarily removes N3-methyladenine but also N3-methylguanine from DNA by glycosylic cleavage in the first step of the base excision repair | Escherichia coli | 3-methyladenine + ? | - |
? | |
| alkylated DNA + H2O | constititively expressed | Escherichia coli | 3-methyladenine + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TAG | - |
Escherichia coli |
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