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Literature summary for 3.2.2.17 extracted from
- Inhibition of enzymic incision of thymine dimers by covalently bound 2-[N-[(Deoxyguanosin-8-yl)acetyl]amino]fluorene in deoxyribonucleic acid (1985), Biochemistry, 24, 408-412.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-[N-(acetoxyacetyl)amino]fluorene | AAAF, carcinogen , extensive modification of DNA does not significantly reduce the thymine dimer yield | Tequatrovirus T4 |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00022 | - |
DNA | arylamidated DNA | Tequatrovirus T4 | |
| 0.00031 | - |
DNA | thymine dimersl | Tequatrovirus T4 | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Tequatrovirus T4 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Tequatrovirus T4 |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA + H2O | strict specificity for DNA cyclobutyldipyrimidines | Tequatrovirus T4 | thymine + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| denV | - |
Tequatrovirus T4 |
| T4 PD-DNA-glycosylase | - |
Tequatrovirus T4 |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 15 | 37 | - |
Tequatrovirus T4 |
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Release 2023.1 (January 2023)
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