Literature summary for 3.2.1.76 extracted from

Breier, A.C.; Ce, J.; Mezzalira, J.; Daitx, V.V.; Moraes, V.C.; Goldim, M.P.S.; Coelho, J.C.
alpha-L-iduronidase and arylsulfatase B in dried blood spots on filter paper Biochemical parameters and time stability (2017), Clin. Biochem., 50, 431-435 .

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General Stability

General Stability	Organism
the enzyme activity significantly decayes starting at 21 days after the filter paper was impregnated with blood	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.48	-	4-methylumbelliferyl alpha-L-iduronide	at pH 2.8 and 37°C	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P35475	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-methylumbelliferyl alpha-L-iduronide + H2O	-	Homo sapiens	4-methylumbelliferone + alpha-L-iduronic acid	-	?

Synonyms

Synonyms	Comment	Organism
alpha-L-iduronidase	-	Homo sapiens
IDUA	-	Homo sapiens

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
2.8	-	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	mucopolysaccharidosis type I is caused by the deficient activity of the enzyme	Homo sapiens

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Release 2023.1 (January 2023)