Literature summary for 3.2.1.76 extracted from

Artola, M.; Kuo, C.L.; McMahon, S.A.; Oehler, V.; Hansen, T.; van der Lienden, M.; He, X.; van den Elst, H.; Florea, B.I.; Kermode, A.R.; van der Marel, G.A.; Gloster, T.M.; Codee, J.D.C.; Overkleeft, H.S.; Aerts, J.M.F.G.
New irreversible alpha-L-iduronidase inhibitors and activity-based probes (2018), Chemistry, 24, 19081-19088 .

Search for more literature for 3.2.1.76

Inhibitors

Inhibitors	Comment	Organism	Structure
(2R,3R,4R,5S)-2-carboxy-3,4,5-trihydroxypiperidine	reversible inhibitor	Homo sapiens
5-fluoro-alpha-L-idopyranosyl uronic acid fluoride	reversible inhibitor	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
lysosome	-	Homo sapiens	5764	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P35475	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-methylumbelliferyl alpha-L-iduronide + H2O	-	Homo sapiens	4-methylumbelliferone + alpha-L-iduronic acid	-	?

Synonyms

Synonyms	Comment	Organism
Aldurazyme	commercial preparation	Homo sapiens
alpha-L-iduronidase	-	Homo sapiens
IDUA	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)