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Literature summary for 3.2.1.76 extracted from

  • Chen, F.; Vitry, S.; Hocquemiller, M.; Desmaris, N.; Ausseil, J.; Heard, J.M.
    Alpha-L-iduronidase transport in neurites (2006), Mol. Genet. Metab., 87, 349-358.
    View publication on PubMed
Search for more literature for 3.2.1.76

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Rattus norvegicus primary neurons using lentivirus vectors Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Homo sapiens 5764
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
74000
-
 SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
neuron
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.018
-
 native enzyme, using 4-methylumbelliferyl-alpha-L-iduronide as a substrate Homo sapiens
0.03
-
 recombinant enzyme, using 4-methylumbelliferyl-alpha-L-iduronide as a substrate Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl-alpha-L-iduronide + H2O
-
 Homo sapiens 4-methylumbelliferone + alpha-L-iduronic acid
-
 ?

Synonyms

Synonyms Comment Organism
alpha-L-iduronidase
-
 Homo sapiens
IDUA
-
 Homo sapiens