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Literature summary for 3.2.1.76 extracted from

  • Rome, L.H.
    alpha-L-Iduronidase from human kidney (1982), Methods Enzymol., 83, 578-583.
    View publication on PubMed
Search for more literature for 3.2.1.76

Activating Compound

Activating Compound Comment Organism Structure
2-mercaptoethanol
-
 Homo sapiens
dithiothreitol
-
 Homo sapiens
glutathione
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
p-chloromercuribenzoate
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.09
-
 4-methylumbelliferyl-alpha-L-iduronide
-
 Homo sapiens
1.5
-
 phenyl alpha-L-iduronide
-
 Homo sapiens
9
-
 anhydromannitol iduronide
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
60000
-
 sedimentation equilibrium Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Homo sapiens
-
urine
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
250
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phenyl alpha-L-iduronide + H2O
-
 Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
dimer
-
 Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4
-
-
 Homo sapiens
4.5
-
 anhydromannitol as substrate Homo sapiens