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Literature summary for 3.2.1.62 extracted from

  • Tanaka, T.; Suzuki, A.; Kuranuki, S.; Mochizuki, K.; Suruga, K.; Takase, S.; Goda, T.
    Higher expression of jejunal LPH gene in rats fed the high-carbohydrate/low-fat diet compared with those fed the low-carbohydrate/high-fat diet is associated with in vitro binding of Cdx-2 in nuclear proteins to its promoter regions (2008), Life Sci., 83, 122-127.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information higher expression and gene transcription of LPH in jejunum of rats fed a high-carbohydrate/low-fat diet compared with those fed a low carbohydrate/high-fat diet. In vitro binding of the caudal homeobox protein Cdx-2, which is important for intestinal gene expression and differentiation, to the homeodomain protein-binding element CE-LPH1 in jejunal nuclear extracts is associated with the higher expression of LPH Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
expressed in CACO-2 cells Rattus norvegicus
LPH 5' upstream subcloned from rat liver genomic DNA Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
Rattus norvegicus 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38000
-
sequence analysis Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
male sprague-dawley rats
-

Source Tissue

Source Tissue Comment Organism Textmining
jejunum
-
Rattus norvegicus
-
liver
-
Rattus norvegicus
-
small intestine
-
Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
lactase-phlorizin hydrolase
-
Rattus norvegicus
LPH1
-
Rattus norvegicus