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Literature summary for 3.2.1.53 extracted from
- Neutral beta-N-acetylhexosaminidases of rat brain. Purification and enzymatic and immunological characterization (1983), J. Biol. Chem., 258, 6991-6999.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| N-acetylgalactosamine | - |
Rattus norvegicus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.42 | - |
4-methylumbelliferyl beta-N-acetylgalactosaminide | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| lysosome | - |
Rattus norvegicus | 5764 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 82000 | - |
sucrose density gradient centrifugation | Rattus norvegicus |
| 210000 | - |
gel filtration | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N-acetyl-beta-D-galactosaminides + H2O | Rattus norvegicus | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
rat | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 9.8 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-methylumbelliferyl beta-N-acetylgalactosaminide + H2O | - |
Rattus norvegicus | 4-methylumbelliferone + N-acetyl-beta-D-galactosamine | - |
? | |
| N-acetyl-beta-D-galactosaminides + H2O | e.g. 4-methylumbelliferyl-beta-N-acetylgalactosaminide | Rattus norvegicus | N-acetyl-D-galactosamine + an alcohol | e.g. 4-methylumbelliferone | ? | |
| N-acetyl-beta-D-galactosaminides + H2O | - |
Rattus norvegicus | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
4-methylumbelliferyl beta-N-acetylgalactosaminide | Rattus norvegicus |
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