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Literature summary for 3.2.1.51 extracted from

  • Piesecki, S.; Alhadeff, J.A.
    The effect of carbohydrate removal on the properties of human liver alpha-L-fucosidase (1992), Biochim. Biophys. Acta, 1119, 194-200.
    View publication on PubMed
Search for more literature for 3.2.1.51

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.26
-
 4-nitrophenyl-alpha-L-fucopyranoside
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Homo sapiens 5764
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fuc-alpha-(1-2)-Gal-beta-(1-4)-Glc + H2O Homo sapiens 2'-fucosyllactose alpha-L-fucose + lactose
-
 ?
GalNAc-alpha-(1-3)-Gal-[Fuc-alpha-(1-2)] + H2O Homo sapiens low activity alpha-L-fucose + GalNAc-alpha-(1-3)-Gal
-
 ?
lacto-N-fucopentaose II + H2O Homo sapiens low activity alpha-L-fucose + Gal-beta-(1-3)-GlcNAc-beta-(1-3)-Gal-beta-(1-4)-Glc
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
to homogeneity, affinity chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl-alpha-L-fucopyranoside + H2O
-
 Homo sapiens 4-nitrophenol + alpha-L-fucose
-
 ?
Fuc-alpha-(1-2)-Gal-beta-(1-4)-Glc + H2O 2'-fucosyllactose Homo sapiens alpha-L-fucose + lactose
-
 ?
GalNAc-alpha-(1-3)-Gal-[Fuc-alpha-(1-2)] + H2O low activity Homo sapiens alpha-L-fucose + GalNAc-alpha-(1-3)-Gal
-
 ?
lacto-N-fucopentaose II + H2O low activity Homo sapiens alpha-L-fucose + Gal-beta-(1-3)-GlcNAc-beta-(1-3)-Gal-beta-(1-4)-Glc
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
50
-
 native enzyme: 80% residual activity after 2 h, deglycosylated enzyme: 38% residual activity after 2 h Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
-
 Homo sapiens
5.4
-
 deglycosylated enzyme Homo sapiens
6.3
-
 second pH-optimum for native and deglycosylated enzymes Homo sapiens