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Literature summary for 3.2.1.50 extracted from

  • Salvatore, D.; Bonatti, S.; Di Natale, P.
    Lysosomal alpha-N-acetylglucosamidase: purification and characterization of the human urinary enzyme (1984), Bull. Mol. Biol. Med., 9, 111-121.
No PubMed abstract available
Search for more literature for 3.2.1.50

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Homo sapiens 5764
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
86000
-
 SDS-PAGE after reduction and alkylation of native enzyme Homo sapiens
240000
-
 native enzyme, sucrose density gradient centrifugation Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(GlcNAcalpha(1-4))n + H2O Homo sapiens
-
 (GlcNAcalpha(1-4))n-1 + 2-(acetylamino)-2-deoxy-beta-D-glucopyranose
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
urine
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.115 1.2 purified enzyme, p-nitrophenyl-N-acetyl-alpha-D-glucosaminide as substrate Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(GlcNAcalpha(1-4))n + H2O
-
 Homo sapiens (GlcNAcalpha(1-4))n-1 + 2-(acetylamino)-2-deoxy-beta-D-glucopyranose
-
 ?
p-nitrophenyl-N-acetyl-alpha-D-glucosaminide + H2O
-
 Homo sapiens p-nitrophenol + N-acetyl-alpha-D-glucosamine
-
 ?

Subunits

Subunits Comment Organism
multimer
-
 Homo sapiens

Synonyms

Synonyms Comment Organism
Sanfilippo b corrective factor previously Homo sapiens