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Literature summary for 3.2.1.48 extracted from
- Impact of glycosylation and detergent-resistant membranes on the function of intestinal sucrase-isomaltase (2009), Biol. Chem., 390, 545-549.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| brush border membrane | the enzyme is sorted with high fidelity to the apical membrane via O-linked glycans that mediate its association with lipid rafts or detergent-resistant membranes | Homo sapiens | 31526 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | the enzyme is highly glycosylated, glycosylation is inhibited by benzyl-GalNAc. Modulation of the glycosylation pattern of the enzyme with benzyl-2-acetamido-2-deoxy-alpha-D-galactopyranoside and deoxymannojirimycin, overview. N- and O-glycosylation and detergent-resistant membranes are implicated in the regulation of the function of the enzyme in intestinal Caco-2 cells | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Caco-2 cell | - |
Homo sapiens | - |
| intestine | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| sucrase-isomaltase | - |
Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
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Release 2023.1 (January 2023)
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