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Literature summary for 3.2.1.48 extracted from

  • Gu, N.; Suzuki, N.; Takeda, J.; Adachi, T.; Tsujimoto, G.; Aoki, N.; Ishihara, A.; Tsuda, K.; Yasuda, K.
    Effect of mutations in HNF-1alpha and HNF-1beta on the transcriptional regulation of human sucrase-isomaltase in Caco-2 cells (2004), Biochem. Biophys. Res. Commun., 325, 308-313.
    View publication on PubMed
Search for more literature for 3.2.1.48

Activating Compound

Activating Compound Comment Organism Structure
additional information transcription factors HNF-1alpha and HNF-1beta transactivate enzyme expression in the small intestine, reduced activation activity of 13 HNF mutants, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme expression is transactivated by transcription factors hepatocyte nuclear factors 1alpha and 1beta, HNF-1alpha and HNF-1beta, molecular mechanism and responsible amino acids of HNFs, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
Caco-2 cell
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 Homo sapiens
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small intestine
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 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme expression is transactivated by transcription factors hepatocyte nuclear factors 1alpha and 1beta, HNF-1alpha and HNF-1beta, molecular mechanism and responsible amino acids of HNFs, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
sucrase-isomaltase
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 Homo sapiens