Application | Comment | Organism |
---|---|---|
medicine | sucrase-isomaltase SI is a marker enzyme of the absorptive villose cells in adult small intestine, human intestinal sucrase-isomaltase help develop a specific inhibitor of sucrase, to retard the absorption of sucrose in the intestinal tract of diabetic patients | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-Amino-2-ethyl-1,3-propanediol | - |
Homo sapiens | |
2-amino-2-methyl-1,3-propanediol | - |
Homo sapiens | |
2-amino-2-methyl-1-propanol | - |
Homo sapiens | |
Bis-Tris | - |
Homo sapiens | |
diethanolamine | - |
Homo sapiens | |
Monoethanolamine | - |
Homo sapiens | |
triethanolamine | - |
Homo sapiens | |
Tris | concentration-dependent biphasic effect, first causing activation, fully competitive inhibition above pH 6.8, inhibition is stronger at alkaline pH values | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
130000 | - |
gel filtration, density gradient, equilibrium centrifugation, sucrase subunit | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
maltose + H2O | Homo sapiens | - |
2 glucose | - |
? | |
sucrose + H2O | Homo sapiens | - |
D-glucose + D-fructose | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
2.32 | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-20°C | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
maltose + H2O | - |
Homo sapiens | 2 glucose | - |
? | |
sucrose + H2O | - |
Homo sapiens | D-glucose + D-fructose | - |
? |