Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Mus musculus | 5764 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-galactosylceramide + H2O | Mus musculus | - |
D-galactose + ceramide | - |
? | |
D-galactosylsphingoside + H2O | Mus musculus | i.e. psychosine | D-galactose + sphingosine | - |
? | |
additional information | Mus musculus | the enzyme is required for normal sperm maturation and function, enzyme deficiency leads to degeneration of oligodendrocytes, severe demyelination, and causes sperm abnormalities in the mouse model of human globoid cell leukodystrophy or Krabbe disease, mutant twitcher mice show reduced size of testis and sperm acrosomal membrane which is redundant, detached from the nucleus and folded over | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
spermatozoon | - |
Mus musculus | - |
testis | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-galactosyl-alkyl-acyl-glycerol + H2O | a precursor of the seminolipid | Mus musculus | ? | - |
? | |
D-galactosylceramide + H2O | - |
Mus musculus | D-galactose + ceramide | - |
? | |
D-galactosylsphingoside + H2O | i.e. psychosine | Mus musculus | D-galactose + sphingosine | - |
? | |
additional information | the enzyme is required for normal sperm maturation and function, enzyme deficiency leads to degeneration of oligodendrocytes, severe demyelination, and causes sperm abnormalities in the mouse model of human globoid cell leukodystrophy or Krabbe disease, mutant twitcher mice show reduced size of testis and sperm acrosomal membrane which is redundant, detached from the nucleus and folded over | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GALC | - |
Mus musculus |