Literature summary for 3.2.1.45 extracted from

Blanz, J.; Groth, J.; Zachos, C.; Wehling, C.; Saftig, P.; Schwake, M.
Disease-causing mutations within the lysosomal integral membrane protein type 2 (LIMP-2) reveal the nature of binding to its ligand beta-glucocerebrosidase (2010), Hum. Mol. Genet., 19, 563-572.

Search for more literature for 3.2.1.45

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
lysosome	LIMP-2 is the receptor for the mannose-6-phosphate independent transport of beta-glucocerebrosidase to the lysosome	Homo sapiens	5764	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
glucosylceramide + H2O	Homo sapiens	-	beta-D-glucose + ceramide	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
fibroblast	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
glucosylceramide + H2O	-	Homo sapiens	beta-D-glucose + ceramide	-	?

Synonyms

Synonyms	Comment	Organism
beta-GC	-	Homo sapiens
beta-glucocerebrosidase	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)