Literature summary for 3.2.1.45 extracted from

Brumshtein, B.; Greenblatt, H.M.; Butters, T.D.; Shaaltiel, Y.; Aviezer, D.; Silman, I.; Futerman, A.H.; Sussman, J.L.
Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid beta-glucosidase: insights into the mechanism of chemical chaperone action in Gaucher disease (2007), J. Biol. Chem., 282, 29052-29058.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in cultured plant cells	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
cocrystallization with inhibitors using the micro-batch technique, with 0.2 M (NH4)2SO4/0.1 M Tris, pH 6.5, 25% (w/v) polyethylene glycol 3350 or 0.2 M NH4COOCH3/0.1 M HEPES, pH 7.5, 25% (w/v) polyethyleneglycol 3350	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
N-butyldeoxynojirimycin	Zavesca	Homo sapiens
N-nonyldeoxynojirimycin	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P04062	-	-

Synonyms

Synonyms	Comment	Organism
acid beta-glucosidase	-	Homo sapiens
GlcCerase	-	Homo sapiens

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Release 2023.1 (January 2023)