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Literature summary for 3.2.1.45 extracted from

  • Maret, A.; Salvayre, R.; Potier, M.; Legler, G.; Beauregard, G.; Douste-Blazy, L.
    Comparison of human membrane-bound beta-glucosidases: lysosomal glucosylceramide-beta-glucosidase and non-specific beta-glucosidase (1988), NATO ASI Ser. A, Life Sci., 150, 57-61.
No PubMed abstract available
Search for more literature for 3.2.1.45

Inhibitors

Inhibitors Comment Organism Structure
(1R,2R,3S,4S,5R,6S)-7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol
-
 Homo sapiens
1-deoxynojirimycin
-
 Homo sapiens
6-bromo-conduritol-beta-epoxide
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Homo sapiens 5764
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
67000
-
 radiation inactivation, normal enzyme Homo sapiens
125000
-
 radiation inactivation, Gaucher disease enzyme Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
spleen
-
 Homo sapiens
-

Subunits

Subunits Comment Organism
monomer 1 * 67000, subunit coupling in Gaucher disease enzyme Homo sapiens

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
42
-
 60 min, 10% loss of activity Homo sapiens
50
-
 60 min, 60% loss of activity Homo sapiens

pH Stability

pH Stability pH Stability Maximum Comment Organism
4
-
 30 min, 10% loss of activity Homo sapiens